265439

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ykfI-yeeU/CbtA-CbeA
Location 2939508..2940234 Replicon chromosome
Accession NZ_CP113163
Organism Citrobacter braakii strain LBA3

Toxin (Protein)


Gene name ykfI Uniprot ID -
Locus tag MKJ05_RS14060 Protein ID WP_134882353.1
Coordinates 2939508..2939849 (-) Length 114 a.a.

Antitoxin (Protein)


Gene name yeeU Uniprot ID -
Locus tag MKJ05_RS14065 Protein ID WP_004129347.1
Coordinates 2939884..2940234 (-) Length 117 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MKJ05_RS14040 (MKJ05_14040) 2934737..2936575 + 1839 WP_267581382.1 pilus assembly protein -
MKJ05_RS14045 (MKJ05_14045) 2936638..2937456 + 819 WP_181013961.1 CZB domain-containing protein -
MKJ05_RS14050 (MKJ05_14050) 2937653..2938351 + 699 WP_114683307.1 CZB domain-containing protein -
MKJ05_RS14055 (MKJ05_14055) 2938522..2938992 + 471 WP_151235961.1 transglycosylase SLT domain-containing protein -
MKJ05_RS14060 (MKJ05_14060) 2939508..2939849 - 342 WP_134882353.1 TA system toxin CbtA family protein Toxin
MKJ05_RS14065 (MKJ05_14065) 2939884..2940234 - 351 WP_004129347.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
MKJ05_RS14070 (MKJ05_14070) 2940255..2940476 - 222 WP_004129348.1 DUF987 domain-containing protein -
MKJ05_RS14075 (MKJ05_14075) 2940492..2940965 - 474 WP_107357770.1 DNA repair protein RadC -
MKJ05_RS14080 (MKJ05_14080) 2941036..2941857 - 822 WP_267589304.1 DUF932 domain-containing protein -
MKJ05_RS14085 (MKJ05_14085) 2941953..2942630 - 678 WP_134882355.1 hypothetical protein -
MKJ05_RS14090 (MKJ05_14090) 2942915..2943808 - 894 WP_107357772.1 50S ribosome-binding GTPase -
MKJ05_RS14095 (MKJ05_14095) 2943907..2945004 - 1098 WP_117031494.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 2918729..2955299 36570


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-108)

Antitoxin

Antitoxin CbeA

(15-115)


Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 12947.97 Da        Isoelectric Point: 5.5865

>T265439 WP_134882353.1 NZ_CP113163:c2939849-2939508 [Citrobacter braakii]
MNTLPAINQWAVQLCPSPVNIWQTLLTRLLEQHYGLALNDTPFGDESVIQEHIDAGITLVDTVNFLVEKYELVRIDRRAF
GWLEPSPYLRAVDILRMRRDMGLLRGCNHTAAM

Download         Length: 342 bp

Antitoxin


Download         Length: 117 a.a.        Molecular weight: 12956.70 Da        Isoelectric Point: 6.9559

>AT265439 WP_004129347.1 NZ_CP113163:c2940234-2939884 [Citrobacter braakii]
MSSKTLTVNDDTAEPWWGLNRNVIPCFGARLVQEGNRLHYLSDRASITGQFNKADLLHLDQAFPVLLKQAELMLTSGELN
PRHQHSVTLYAKGLTCEADTLGSCGHVYISIYPTQR

Download         Length: 351 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References