Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) pezAT/zeta-ParD
Location 4911094..4912097 Replicon chromosome
Accession NZ_CP113116
Organism Mycobacterium sp. Aquia_213

Toxin (Protein)


Gene name pezT Uniprot ID -
Locus tag LMQ14_RS22720 Protein ID WP_267731812.1
Coordinates 4911094..4911672 (-) Length 193 a.a.

Antitoxin (Protein)


Gene name pezA Uniprot ID -
Locus tag LMQ14_RS22725 Protein ID WP_267731813.1
Coordinates 4911669..4912097 (-) Length 143 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LMQ14_RS22700 (LMQ14_22700) 4906819..4907700 - 882 WP_267731808.1 DUF4436 domain-containing protein -
LMQ14_RS22705 (LMQ14_22705) 4907693..4909558 - 1866 WP_267731809.1 glutamine--fructose-6-phosphate transaminase (isomerizing) -
LMQ14_RS22710 (LMQ14_22710) 4909777..4910235 + 459 WP_267731810.1 DUF2510 domain-containing protein -
LMQ14_RS22715 (LMQ14_22715) 4910245..4911084 + 840 WP_267731811.1 dienelactone hydrolase family protein -
LMQ14_RS22720 (LMQ14_22720) 4911094..4911672 - 579 WP_267731812.1 zeta toxin family protein Toxin
LMQ14_RS22725 (LMQ14_22725) 4911669..4912097 - 429 WP_267731813.1 hypothetical protein Antitoxin
LMQ14_RS22730 (LMQ14_22730) 4912214..4913257 + 1044 WP_267731814.1 LLM class F420-dependent oxidoreductase -
LMQ14_RS22735 (LMQ14_22735) 4913262..4914650 - 1389 WP_267731815.1 hypothetical protein -
LMQ14_RS22740 (LMQ14_22740) 4914653..4914970 - 318 WP_267731816.1 type VII secretion target -
LMQ14_RS22745 (LMQ14_22745) 4915018..4916355 - 1338 WP_267731817.1 phosphoglucosamine mutase -
LMQ14_RS22750 (LMQ14_22750) 4916502..4916975 - 474 WP_267735642.1 30S ribosomal protein S9 -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 193 a.a.        Molecular weight: 21141.26 Da        Isoelectric Point: 10.0916

>T265430 WP_267731812.1 NZ_CP113116:c4911672-4911094 [Mycobacterium sp. Aquia_213]
MNRLDLVVGPNGAGKSTFVEFTLAPLLPTSVFVNADEIARQRWPADAAAHSYEAARIAAGTRARLIELRRSFIAETVFSH
PSKLELIDSAHAASYTVVLHVLLIPEKLAVERVKHRVAAGGHDVPEAKIRQRYQRLWPLVVTAVARCDSATVYDNSALKG
PRIVAQMSFGQPDGTPTWPAWTPRELTSRWPA

Download         Length: 579 bp


Antitoxin


Download         Length: 143 a.a.        Molecular weight: 15129.85 Da        Isoelectric Point: 10.2543

>AT265430 WP_267731813.1 NZ_CP113116:c4912097-4911669 [Mycobacterium sp. Aquia_213]
MADSADRVTRFAADLVDSAKAEGARQSRSAKQQLDHWARVGRAVSSQHSAARRRVEAALAGDLELGELSVEEGVVFNAEI
AAAIQENLNQANYGKLLAKRGVTTVALNEAGEIVEHRPDGSSTVLTANSRPARRKKVNAGAR

Download         Length: 429 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References