Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PP_4151-4152/excise(antitoxin)
Location 5080049..5081088 Replicon chromosome
Accession NZ_CP113097
Organism Pseudomonas putida strain WYTS.T61

Toxin (Protein)


Gene name PP_4152 Uniprot ID -
Locus tag OSW16_RS23380 Protein ID WP_267818864.1
Coordinates 5080049..5080624 (-) Length 192 a.a.

Antitoxin (Protein)


Gene name PP_4151 Uniprot ID -
Locus tag OSW16_RS23385 Protein ID WP_267818866.1
Coordinates 5080624..5081088 (-) Length 155 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OSW16_RS23355 (OSW16_23355) 5075660..5076472 + 813 WP_241807191.1 alpha/beta fold hydrolase -
OSW16_RS23360 (OSW16_23360) 5076465..5077637 + 1173 WP_267818860.1 MFS transporter -
OSW16_RS23365 (OSW16_23365) 5078818..5078987 - 170 Protein_4602 plasmid pRiA4b ORF-3 family protein -
OSW16_RS23370 (OSW16_23370) 5079188..5079637 + 450 WP_267818862.1 GNAT family N-acetyltransferase -
OSW16_RS23375 (OSW16_23375) 5079698..5079932 - 235 Protein_4604 transposase -
OSW16_RS23380 (OSW16_23380) 5080049..5080624 - 576 WP_267818864.1 PIN domain-containing protein Toxin
OSW16_RS23385 (OSW16_23385) 5080624..5081088 - 465 WP_267818866.1 helix-turn-helix domain-containing protein Antitoxin
OSW16_RS23390 (OSW16_23390) 5081692..5081889 - 198 WP_267818868.1 Arm DNA-binding domain-containing protein -
OSW16_RS23395 (OSW16_23395) 5082794..5083690 + 897 WP_267818870.1 hypothetical protein -
OSW16_RS23400 (OSW16_23400) 5083677..5085548 + 1872 WP_267818872.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(8-115)

Antitoxin

SinI-like, DNA-binding domain

(84-130)


Sequences

Toxin        


Download         Length: 192 a.a.        Molecular weight: 21932.30 Da        Isoelectric Point: 5.6011

>T265402 WP_267818864.1 NZ_CP113097:c5080624-5080049 [Pseudomonas putida]
MRHSPFTVIYDACVLYPAPLRDLLMHLALTGAYRARWSGQIHEEWTRNVLKNRSDLTKAQLDRTVEAMNRAVPDCLVNDY
EPLIQGLDLPDEDDRHVLAAAIKCGASVIVTYNLKDFPAEILMRFEIEALHPDVFLSDIWDLDQAAVLEAVQKQRASLKN
PRYTPRELLDTLLKQRLPEIVKHLSSYELLI

Download         Length: 576 bp

Antitoxin


Download         Length: 155 a.a.        Molecular weight: 16922.30 Da        Isoelectric Point: 5.6386

>AT265402 WP_267818866.1 NZ_CP113097:c5081088-5080624 [Pseudomonas putida]
MTTADLARSILPDEKAIAAATESSRQIAAFVSTKLDTQRIELVDEAQQRQTVELPTFALRLLGDILNELALGNTVKVVPI
HAELTTQEGADMLNVSRPHLVKLLDEGQIPHTKTGSHRRIKFTDIMAYKADRDRASQAAMEELAAQAQALNMGY

Download         Length: 465 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References