Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-higA/HigB-HigA
Location 550623..551491 Replicon chromosome
Accession NZ_CP113097
Organism Pseudomonas putida strain WYTS.T61

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag OSW16_RS02565 Protein ID WP_267820524.1
Coordinates 551138..551491 (-) Length 118 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag OSW16_RS02560 Protein ID WP_267820522.1
Coordinates 550623..551096 (-) Length 158 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OSW16_RS02535 (OSW16_02535) 546492..546983 - 492 WP_267820514.1 hypothetical protein -
OSW16_RS02540 (OSW16_02540) 547190..548842 + 1653 WP_267820516.1 flavin monoamine oxidase family protein -
OSW16_RS02545 (OSW16_02545) 549051..549602 + 552 WP_267820518.1 cytochrome b -
OSW16_RS02550 (OSW16_02550) 549634..550212 + 579 WP_267820520.1 YceI family protein -
OSW16_RS02555 (OSW16_02555) 550261..550549 - 289 Protein_509 IS4 family transposase -
OSW16_RS02560 (OSW16_02560) 550623..551096 - 474 WP_267820522.1 transcriptional regulator Antitoxin
OSW16_RS02565 (OSW16_02565) 551138..551491 - 354 WP_267820524.1 type II toxin-antitoxin system HigB family toxin Toxin
OSW16_RS02570 (OSW16_02570) 551706..551853 - 148 Protein_512 IS4 family transposase -
OSW16_RS02575 (OSW16_02575) 551976..553868 - 1893 WP_267820526.1 DEAD/DEAH box helicase -
OSW16_RS02580 (OSW16_02580) 554085..554873 - 789 WP_267820528.1 transporter substrate-binding domain-containing protein -
OSW16_RS02585 (OSW16_02585) 554950..556026 - 1077 WP_267820530.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, mRNA interferase HigB

(74-111)

Antitoxin

Antitoxin HigA

(43-154)


Sequences

Toxin        


Download         Length: 118 a.a.        Molecular weight: 13754.94 Da        Isoelectric Point: 10.5584

>T265400 WP_267820524.1 NZ_CP113097:c551491-551138 [Pseudomonas putida]
MRVITKAAVTKAIEAHGQWKAPLSLWLTTFDRATLRFESFEQLRQTWTTVSGWNVDRIPYSRLRPPSRKGPLDIYVFDIK
KNECRLIAWLNARTGTLYIKAILSHAEYDKWCRSDIR

Download         Length: 354 bp

Antitoxin


Download         Length: 158 a.a.        Molecular weight: 17154.60 Da        Isoelectric Point: 4.5641

>AT265400 WP_267820522.1 NZ_CP113097:c551096-550623 [Pseudomonas putida]
MKRDKVEANGLDAFIANISPMLDGLNTQMATMAQLLAACHDPIKDDAELEARMALIDELYSHADSEGHAAARFAEMVADR
VYAYESDSVLVPFASQAEALAFLLADRGVKQKDLSAIATQSAVSEILNNKRKMTVAQIKGFAEFFNVPVEFFMHGVV

Download         Length: 474 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References