Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relE-higA/HigB-HigA |
Location | 550623..551491 | Replicon | chromosome |
Accession | NZ_CP113097 | ||
Organism | Pseudomonas putida strain WYTS.T61 |
Toxin (Protein)
Gene name | relE | Uniprot ID | - |
Locus tag | OSW16_RS02565 | Protein ID | WP_267820524.1 |
Coordinates | 551138..551491 (-) | Length | 118 a.a. |
Antitoxin (Protein)
Gene name | higA | Uniprot ID | - |
Locus tag | OSW16_RS02560 | Protein ID | WP_267820522.1 |
Coordinates | 550623..551096 (-) | Length | 158 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
OSW16_RS02535 (OSW16_02535) | 546492..546983 | - | 492 | WP_267820514.1 | hypothetical protein | - |
OSW16_RS02540 (OSW16_02540) | 547190..548842 | + | 1653 | WP_267820516.1 | flavin monoamine oxidase family protein | - |
OSW16_RS02545 (OSW16_02545) | 549051..549602 | + | 552 | WP_267820518.1 | cytochrome b | - |
OSW16_RS02550 (OSW16_02550) | 549634..550212 | + | 579 | WP_267820520.1 | YceI family protein | - |
OSW16_RS02555 (OSW16_02555) | 550261..550549 | - | 289 | Protein_509 | IS4 family transposase | - |
OSW16_RS02560 (OSW16_02560) | 550623..551096 | - | 474 | WP_267820522.1 | transcriptional regulator | Antitoxin |
OSW16_RS02565 (OSW16_02565) | 551138..551491 | - | 354 | WP_267820524.1 | type II toxin-antitoxin system HigB family toxin | Toxin |
OSW16_RS02570 (OSW16_02570) | 551706..551853 | - | 148 | Protein_512 | IS4 family transposase | - |
OSW16_RS02575 (OSW16_02575) | 551976..553868 | - | 1893 | WP_267820526.1 | DEAD/DEAH box helicase | - |
OSW16_RS02580 (OSW16_02580) | 554085..554873 | - | 789 | WP_267820528.1 | transporter substrate-binding domain-containing protein | - |
OSW16_RS02585 (OSW16_02585) | 554950..556026 | - | 1077 | WP_267820530.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 118 a.a. Molecular weight: 13754.94 Da Isoelectric Point: 10.5584
>T265400 WP_267820524.1 NZ_CP113097:c551491-551138 [Pseudomonas putida]
MRVITKAAVTKAIEAHGQWKAPLSLWLTTFDRATLRFESFEQLRQTWTTVSGWNVDRIPYSRLRPPSRKGPLDIYVFDIK
KNECRLIAWLNARTGTLYIKAILSHAEYDKWCRSDIR
MRVITKAAVTKAIEAHGQWKAPLSLWLTTFDRATLRFESFEQLRQTWTTVSGWNVDRIPYSRLRPPSRKGPLDIYVFDIK
KNECRLIAWLNARTGTLYIKAILSHAEYDKWCRSDIR
Download Length: 354 bp
Antitoxin
Download Length: 158 a.a. Molecular weight: 17154.60 Da Isoelectric Point: 4.5641
>AT265400 WP_267820522.1 NZ_CP113097:c551096-550623 [Pseudomonas putida]
MKRDKVEANGLDAFIANISPMLDGLNTQMATMAQLLAACHDPIKDDAELEARMALIDELYSHADSEGHAAARFAEMVADR
VYAYESDSVLVPFASQAEALAFLLADRGVKQKDLSAIATQSAVSEILNNKRKMTVAQIKGFAEFFNVPVEFFMHGVV
MKRDKVEANGLDAFIANISPMLDGLNTQMATMAQLLAACHDPIKDDAELEARMALIDELYSHADSEGHAAARFAEMVADR
VYAYESDSVLVPFASQAEALAFLLADRGVKQKDLSAIATQSAVSEILNNKRKMTVAQIKGFAEFFNVPVEFFMHGVV
Download Length: 474 bp
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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