Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /Acetyltransf_4(toxin)
Location 6827301..6828740 Replicon chromosome
Accession NZ_CP113096
Organism Pseudomonas citronellolis strain G5Li.T10

Toxin (Protein)


Gene name - Uniprot ID W5IXK4
Locus tag OSS47_RS30360 Protein ID WP_009620564.1
Coordinates 6828171..6828740 (-) Length 190 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID A0A1A5DB74
Locus tag OSS47_RS30355 Protein ID WP_058490851.1
Coordinates 6827301..6828161 (-) Length 287 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OSS47_RS30335 (OSS47_30335) 6822775..6823713 + 939 WP_267853195.1 bile acid:sodium symporter family protein -
OSS47_RS30340 (OSS47_30340) 6823834..6824148 + 315 WP_009620556.1 quaternary ammonium compound efflux SMR transporter SugE -
OSS47_RS30345 (OSS47_30345) 6824340..6824549 + 210 WP_009620558.1 cold-shock protein -
OSS47_RS30350 (OSS47_30350) 6824599..6826473 - 1875 WP_267853196.1 MFS transporter -
OSS47_RS30355 (OSS47_30355) 6827301..6828161 - 861 WP_058490851.1 AraC family transcriptional regulator Antitoxin
OSS47_RS30360 (OSS47_30360) 6828171..6828740 - 570 WP_009620564.1 GNAT family protein Toxin
OSS47_RS30365 (OSS47_30365) 6828992..6832468 + 3477 WP_043271082.1 hybrid sensor histidine kinase/response regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(14-146)

Antitoxin

DNA binding HTH domain, AraC-type

(197-274)


Sequences

Toxin        


Download         Length: 190 a.a.        Molecular weight: 21064.37 Da        Isoelectric Point: 10.2120

>T265398 WP_009620564.1 NZ_CP113096:c6828740-6828171 [Pseudomonas citronellolis]
MFRPSPITLQRGALRLEPMVEADVPDLVALAEANREALKFMSAPQRPDWYRNSLAEQREGRALPLVVRLGNQLVGTTRFM
DFLPALPACEIGGTWLDAAQHGTGLNASIKYLMLRQAFDNWKMVRVQLKTAASNLRSQRAIEKLGAVREGVLRNHRRLAG
GRLDDSVLYSITDLEWPQVKAALEAGFIG

Download         Length: 570 bp

Antitoxin


Download         Length: 287 a.a.        Molecular weight: 31636.99 Da        Isoelectric Point: 8.7317

>AT265398 WP_058490851.1 NZ_CP113096:c6828161-6827301 [Pseudomonas citronellolis]
MPLDSAHGERTRFWRAQELGGLELLHARFIEQRFAPHVHEGFALVLIEQGAQRFRHRGAEHLAPSGSLVLINPDEVHTGS
KAHEAGWLYRGFYPEIGQVGSVLDELELGGRGLPTFDASVLHDPELSRAFLHVHRLLESNASSLERQTCWREALLLLFQR
HARVPEARPAGQEPQAVARARELLAARLVEPPSLEELAAAVNLSPFHFARVFRKATGLPPHAWIKQRRLEQARALLKGGC
APASVAAQLGYADQSHLSRQFKQAYGVAPGEYRQACGRSGLPPGNL

Download         Length: 861 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1A5DB72

Antitoxin

Source ID Structure
AlphaFold DB A0A1A5DB74

References