Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 3368593..3369236 Replicon chromosome
Accession NZ_CP113096
Organism Pseudomonas citronellolis strain G5Li.T10

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag OSS47_RS15400 Protein ID WP_267853822.1
Coordinates 3368593..3369006 (-) Length 138 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID W5IS21
Locus tag OSS47_RS15405 Protein ID WP_009620639.1
Coordinates 3369006..3369236 (-) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OSS47_RS15380 (OSS47_15380) 3363936..3365258 - 1323 WP_267853820.1 aminotransferase class III-fold pyridoxal phosphate-dependent enzyme -
OSS47_RS15385 (OSS47_15385) 3365255..3366319 - 1065 WP_267853821.1 phosphotransferase -
OSS47_RS15390 (OSS47_15390) 3366472..3367206 + 735 WP_009620642.1 SDR family oxidoreductase -
OSS47_RS15395 (OSS47_15395) 3367270..3367959 + 690 WP_061560910.1 GntR family transcriptional regulator -
OSS47_RS15400 (OSS47_15400) 3368593..3369006 - 414 WP_267853822.1 tRNA(fMet)-specific endonuclease VapC Toxin
OSS47_RS15405 (OSS47_15405) 3369006..3369236 - 231 WP_009620639.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
OSS47_RS15410 (OSS47_15410) 3369369..3370070 - 702 WP_009620638.1 ATP-binding cassette domain-containing protein -
OSS47_RS15415 (OSS47_15415) 3370074..3370841 - 768 WP_009620637.1 high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivG -
OSS47_RS15420 (OSS47_15420) 3370838..3372091 - 1254 WP_043314177.1 high-affinity branched-chain amino acid ABC transporter permease LivM -
OSS47_RS15425 (OSS47_15425) 3372088..3373008 - 921 WP_009620635.1 high-affinity branched-chain amino acid ABC transporter permease LivH -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-124)

Antitoxin

SpoVT-AbrB domain

(7-50)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 15167.46 Da        Isoelectric Point: 6.6409

>T265395 WP_267853822.1 NZ_CP113096:c3369006-3368593 [Pseudomonas citronellolis]
MLKFMLDTNICIFTIKNKPQVVREAFNQHHGQLAISSVTLMELIYGAEKSSMPEHNLGIVEGFAARLEVLDYDGNAAAHT
GQLRAELARIGKPIGPYDQMIAGHARSRGLILVSNNLREFEQVPGLRLEDWTVAPSP

Download         Length: 414 bp

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8523.43 Da        Isoelectric Point: 4.3094

>AT265395 WP_009620639.1 NZ_CP113096:c3369236-3369006 [Pseudomonas citronellolis]
MEQGAVFQSNRSQAVRLPKAVALPEDVKRVDVVAIGRTRILTPAGESWDSWFDGENVSADFMSEREQPAEQEREGF

Download         Length: 231 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A1A5DDH0

References