Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tad-ata/COG5606-COG4679
Location 2481151..2481769 Replicon chromosome
Accession NZ_CP113096
Organism Pseudomonas citronellolis strain G5Li.T10

Toxin (Protein)


Gene name tad Uniprot ID A0A1A9KN07
Locus tag OSS47_RS11210 Protein ID WP_058073322.1
Coordinates 2481151..2481456 (+) Length 102 a.a.

Antitoxin (Protein)


Gene name ata Uniprot ID -
Locus tag OSS47_RS11215 Protein ID WP_043269347.1
Coordinates 2481449..2481769 (+) Length 107 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OSS47_RS11185 (OSS47_11185) 2476160..2476885 + 726 WP_043269359.1 alpha/beta fold hydrolase -
OSS47_RS11190 (OSS47_11190) 2476878..2477684 + 807 WP_043269357.1 malonyl-ACP O-methyltransferase BioC -
OSS47_RS11195 (OSS47_11195) 2477835..2478524 + 690 WP_009615494.1 dethiobiotin synthase -
OSS47_RS11200 (OSS47_11200) 2478591..2478818 + 228 WP_009615495.1 hypothetical protein -
OSS47_RS11205 (OSS47_11205) 2479123..2480928 + 1806 WP_043319187.1 phenylacyl-CoA dehydrogenase -
OSS47_RS11210 (OSS47_11210) 2481151..2481456 + 306 WP_058073322.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OSS47_RS11215 (OSS47_11215) 2481449..2481769 + 321 WP_043269347.1 helix-turn-helix transcriptional regulator Antitoxin
OSS47_RS11220 (OSS47_11220) 2481939..2483735 + 1797 WP_043319190.1 acyl-CoA dehydrogenase C-terminal domain-containing protein -
OSS47_RS11225 (OSS47_11225) 2483954..2485732 + 1779 WP_043319192.1 acyl-CoA dehydrogenase C-terminal domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - pilT / pilU / pilG / pilH / pilI / pilJ / pilK / chpB / chpC / chpD / chpE / acrB 2266075..2513008 246933


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(1-89)

Antitoxin

Cro/C1-type helix-turn-helix domain

(30-85)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11249.67 Da        Isoelectric Point: 7.0609

>T265390 WP_058073322.1 NZ_CP113096:2481151-2481456 [Pseudomonas citronellolis]
MPDDVQDVFGFALHQAQEGGKHPQAKPMKGFSGAGVLEVVEDHDGDTYRAVYTVKFARAVYALHCFQKKSTKGIETPQHD
LELIRKRLKDAQAHAKSVEND

Download         Length: 306 bp

Antitoxin


Download         Length: 107 a.a.        Molecular weight: 11579.49 Da        Isoelectric Point: 10.4649

>AT265390 WP_043269347.1 NZ_CP113096:2481449-2481769 [Pseudomonas citronellolis]
MIEFEEGSGNVYADLGRADAGEMQVKARLASKIGSIIKARHLTQTQAAEILGLPQPKVSDMLRGKFRGISEAKMIDCLAR
LGRDVQIVVKAAPRSRREGRVEVVFA

Download         Length: 321 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1A9KN07

Antitoxin

Source ID Structure

References