Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 1943392..1943626 | Replicon | chromosome |
| Accession | NC_017328 | ||
| Organism | Shigella flexneri 2002017 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 1943393..1943496 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 1943392..1943626 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| SFXV_RS10750 | 1938838..1939305 | - | 468 | Protein_1973 | DNA-binding transcriptional regulator PgrR | - |
| SFXV_RS10755 | 1939369..1939679 | + | 311 | Protein_1974 | transposase | - |
| SFXV_RS28200 | 1939722..1940917 | - | 1196 | Protein_1975 | IS3 family transposase | - |
| SFXV_RS10775 | 1940972..1941820 | + | 849 | Protein_1976 | IS3-like element IS600 family transposase | - |
| SFXV_RS28205 | 1941937..1942218 | + | 282 | WP_005127484.1 | excisionase | - |
| SFXV_RS32105 | 1942184..1943261 | + | 1078 | Protein_1978 | phage integrase Arm DNA-binding domain-containing protein | - |
| - | 1943392..1943626 | + | 235 | - | - | Antitoxin |
| - | 1943393..1943496 | - | 104 | - | - | Toxin |
| SFXV_RS10790 | 1943654..1943995 | - | 342 | WP_000976476.1 | YebY family protein | - |
| SFXV_RS28220 | 1944008..1944880 | - | 873 | Protein_1980 | copper homeostasis membrane protein CopD | - |
| SFXV_RS10805 | 1944884..1945258 | - | 375 | WP_000168747.1 | CopC domain-containing protein YobA | - |
| SFXV_RS10810 | 1945397..1945627 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| SFXV_RS10815 | 1945729..1946385 | + | 657 | Protein_1983 | carbon-nitrogen hydrolase family protein | - |
| SFXV_RS10820 | 1946409..1947071 | + | 663 | WP_000944268.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T26538 NC_017328:c1943496-1943393 [Shigella flexneri 2002017]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT26538 NC_017328:1943392-1943626 [Shigella flexneri 2002017]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
