Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 4683947..4684599 Replicon chromosome
Accession NZ_CP113083
Organism Rhodopseudomonas palustris strain CGA0092

Toxin (Protein)


Gene name vapC Uniprot ID Q6N2A8
Locus tag OR798_RS21475 Protein ID WP_011159677.1
Coordinates 4684195..4684599 (+) Length 135 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID Q6N2A9
Locus tag OR798_RS21470 Protein ID WP_011159676.1
Coordinates 4683947..4684198 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OR798_RS21460 (OR798_21460) 4679109..4679492 - 384 WP_011159673.1 phasin -
OR798_RS21465 (OR798_21465) 4679817..4683398 + 3582 WP_042441275.1 histidine kinase dimerization/phospho-acceptor domain-containing protein -
OR798_RS21470 (OR798_21470) 4683947..4684198 + 252 WP_011159676.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
OR798_RS21475 (OR798_21475) 4684195..4684599 + 405 WP_011159677.1 type II toxin-antitoxin system VapC family toxin Toxin
OR798_RS21480 (OR798_21480) 4684683..4685393 + 711 WP_011159678.1 Crp/Fnr family transcriptional regulator -
OR798_RS21485 (OR798_21485) 4685366..4685590 - 225 WP_011159679.1 DUF1858 domain-containing protein -
OR798_RS21490 (OR798_21490) 4685828..4686940 + 1113 WP_011159680.1 copper-containing nitrite reductase -
OR798_RS21495 (OR798_21495) 4687109..4687990 + 882 WP_011159681.1 SUMF1/EgtB/PvdO family nonheme iron enzyme -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-126)

Antitoxin

Antitoxin VapB-like

(1-82)


Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 14406.53 Da        Isoelectric Point: 4.8780

>T265373 WP_011159677.1 NZ_CP113083:4684195-4684599 [Rhodopseudomonas palustris]
VIVIDTSAIIAIFREEPEAAQFARLIASDDQPVLSSGNLLETAIVLRGLKDIQPAKAERWLDDFIAEAGIRIEPVTTEQA
GYARSAHLRFGKGTGHKAALNYGDCFAYALAKALNAPLLCKGNDFPLTDIPLVA

Download         Length: 405 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9293.42 Da        Isoelectric Point: 6.7249

>AT265373 WP_011159676.1 NZ_CP113083:4683947-4684198 [Rhodopseudomonas palustris]
MHLNIKNDEAHQLATELARMTGESLTAAVTNALREQLAREHRRRQTDQIAQRLLKIGGRYAALPDTGRTPDEILGYDENG
LPT

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB Q6N2A8

Antitoxin

Source ID Structure
AlphaFold DB Q6N2A9

References