Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 4675167..4675952 Replicon chromosome
Accession NZ_CP113083
Organism Rhodopseudomonas palustris strain CGA0092

Toxin (Protein)


Gene name tacT Uniprot ID Q6N2B5
Locus tag OR798_RS21430 Protein ID WP_011159670.1
Coordinates 4675167..4675664 (-) Length 166 a.a.

Antitoxin (Protein)


Gene name tacA Uniprot ID -
Locus tag OR798_RS21435 Protein ID WP_042441274.1
Coordinates 4675665..4675952 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OR798_RS21400 (OR798_21400) 4670288..4670638 + 351 WP_011159664.1 helix-turn-helix transcriptional regulator -
OR798_RS21405 (OR798_21405) 4670635..4671528 + 894 WP_011159665.1 ImmA/IrrE family metallo-endopeptidase -
OR798_RS21410 (OR798_21410) 4671743..4672207 - 465 WP_011159666.1 CopG family transcriptional regulator -
OR798_RS21415 (OR798_21415) 4672217..4674211 - 1995 WP_011159667.1 conjugal transfer protein TraG -
OR798_RS21420 (OR798_21420) 4674345..4674644 - 300 WP_011159668.1 DUF2285 domain-containing protein -
OR798_RS21425 (OR798_21425) 4674752..4675030 + 279 WP_011159669.1 helix-turn-helix transcriptional regulator -
OR798_RS21430 (OR798_21430) 4675167..4675664 - 498 WP_011159670.1 GNAT family N-acetyltransferase Toxin
OR798_RS21435 (OR798_21435) 4675665..4675952 - 288 WP_042441274.1 DUF1778 domain-containing protein Antitoxin
OR798_RS21440 (OR798_21440) 4676023..4676253 - 231 Protein_4244 DUF3363 domain-containing protein -
OR798_RS21445 (OR798_21445) 4676284..4677849 + 1566 WP_065814273.1 DNA topoisomerase -
OR798_RS21455 (OR798_21455) 4678454..4678885 - 432 WP_011159672.1 phasin -
OR798_RS21460 (OR798_21460) 4679109..4679492 - 384 WP_011159673.1 phasin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(38-142)

Antitoxin

Vibrio phage ICP1, Orf50

(9-84)


Sequences

Toxin        


Download         Length: 166 a.a.        Molecular weight: 18315.15 Da        Isoelectric Point: 8.8691

>T265372 WP_011159670.1 NZ_CP113083:c4675664-4675167 [Rhodopseudomonas palustris]
MTFRIEKLRREHHVEGFDCGKEPLNRFLLRYALQSQLSNSSQTYLALSQDEVVGFYTLAFGDVSYEDAPERLRKGVARHP
IPLMILARLAVASAWAGKGIGAGLLKDALARTLAAAEIAGLRAFAVHAKDDQARAFYERFDFIASPSDPMHLFVLLKDVR
ALIGP

Download         Length: 498 bp

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10492.91 Da        Isoelectric Point: 5.1425

>AT265372 WP_042441274.1 NZ_CP113083:c4675952-4675665 [Rhodopseudomonas palustris]
MANAIRSEKLDLRLTPEAKRLLNAAAQASRRSVSEFVLESALDRAQEALPDRQHFGLDAAGWEAFLAALDAPARPLPRLQ
RLLTEPSVFEQAPTE

Download         Length: 288 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB Q6N2B5

Antitoxin

Source ID Structure

References