Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ataRT/DUF1778(antitoxin)
Location 4046762..4047618 Replicon chromosome
Accession NZ_CP113083
Organism Rhodopseudomonas palustris strain CGA0092

Toxin (Protein)


Gene name ataT Uniprot ID Q6N3W1
Locus tag OR798_RS18565 Protein ID WP_011159121.1
Coordinates 4046762..4047292 (-) Length 177 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID Q6N3W0
Locus tag OR798_RS18570 Protein ID WP_011159122.1
Coordinates 4047280..4047618 (-) Length 113 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OR798_RS18545 (OR798_18545) 4041988..4043988 + 2001 WP_011159117.1 phosphomethylpyrimidine synthase ThiC -
OR798_RS18550 (OR798_18550) 4044159..4045034 + 876 WP_011159118.1 DUF4393 domain-containing protein -
OR798_RS18555 (OR798_18555) 4045292..4046475 + 1184 WP_085977287.1 IS3-like element ISRpa2 family transposase -
OR798_RS18560 (OR798_18560) 4046498..4046641 - 144 Protein_3669 DUF6429 family protein -
OR798_RS18565 (OR798_18565) 4046762..4047292 - 531 WP_011159121.1 GNAT family N-acetyltransferase Toxin
OR798_RS18570 (OR798_18570) 4047280..4047618 - 339 WP_011159122.1 DUF1778 domain-containing protein Antitoxin
OR798_RS18575 (OR798_18575) 4047797..4048576 + 780 WP_011159123.1 hypothetical protein -
OR798_RS18580 (OR798_18580) 4048764..4049276 - 513 WP_011159124.1 hypothetical protein -
OR798_RS18585 (OR798_18585) 4049584..4050003 - 420 WP_234803278.1 hypothetical protein -
OR798_RS18590 (OR798_18590) 4051246..4051530 + 285 WP_011159126.1 hypothetical protein -
OR798_RS18595 (OR798_18595) 4051700..4051888 + 189 WP_042441214.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(50-151)

Antitoxin

Vibrio phage ICP1, Orf50

(31-107)


Sequences

Toxin        


Download         Length: 177 a.a.        Molecular weight: 18929.60 Da        Isoelectric Point: 7.7009

>T265371 WP_011159121.1 NZ_CP113083:c4047292-4046762 [Rhodopseudomonas palustris]
MADIDDAPNQPRSRLSAPVPLTIAHDLSAFDCGEPVLNDWLRQRALKNESRFSRTYVVCEGNQVVGYFCVSAGAVERAAA
PGKVRRNAPDAIPVSVIGRLAVSRSHAGIGLGADLLSDALRRIALASQSIGIGAVQVHAKDDAAKRFYLRCAEFIEYPQD
SRTLFLPIETVVAALS

Download         Length: 531 bp

Antitoxin


Download         Length: 113 a.a.        Molecular weight: 12160.97 Da        Isoelectric Point: 11.4488

>AT265371 WP_011159122.1 NZ_CP113083:c4047618-4047280 [Rhodopseudomonas palustris]
MAKSRGAPAKSARRSAAAAARGATSDAKGSINLRIETGTRQLIDDAAAVLGKTRTEFMVESARRQAVDVLLDQRLFTLDP
ERYDAFMQALDNPPAPGPKLKALLRRVPAWRT

Download         Length: 339 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB Q6N3W1

Antitoxin

Source ID Structure
AlphaFold DB Q6N3W0

References