Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN-MazE
Location 3932745..3933400 Replicon chromosome
Accession NZ_CP113083
Organism Rhodopseudomonas palustris strain CGA0092

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag OR798_RS18035 Protein ID WP_042441199.1
Coordinates 3932745..3933149 (-) Length 135 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag OR798_RS18040 Protein ID WP_042441643.1
Coordinates 3933146..3933400 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OR798_RS18020 (OR798_18020) 3927760..3928002 - 243 WP_011159021.1 hypothetical protein -
OR798_RS18025 (OR798_18025) 3928339..3929562 + 1224 WP_011159022.1 efflux RND transporter periplasmic adaptor subunit -
OR798_RS18030 (OR798_18030) 3929565..3932702 + 3138 WP_011159023.1 multidrug efflux RND transporter permease subunit -
OR798_RS18035 (OR798_18035) 3932745..3933149 - 405 WP_042441199.1 PIN domain-containing protein Toxin
OR798_RS18040 (OR798_18040) 3933146..3933400 - 255 WP_042441643.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
OR798_RS18050 (OR798_18050) 3933855..3933986 + 132 WP_267793647.1 hypothetical protein -
OR798_RS18055 (OR798_18055) 3933997..3935190 - 1194 WP_011159025.1 CoA transferase -
OR798_RS18060 (OR798_18060) 3935300..3936511 - 1212 WP_011159026.1 ABC transporter substrate-binding protein -
OR798_RS18065 (OR798_18065) 3936760..3937374 - 615 WP_011159027.1 class I SAM-dependent methyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-115)

Antitoxin

SpoVT-AbrB domain

(5-34)


Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 14748.64 Da        Isoelectric Point: 5.8886

>T265370 WP_042441199.1 NZ_CP113083:c3933149-3932745 [Rhodopseudomonas palustris]
VRAFFDTNILVYSTTSDPRQATAAACLEQGGFASVQVLNEFVHVARRKLRHDWPQIEVALEQFHAALDDVLPITLTTHAA
AVVLARDHRVSFYDALIVAAAQAAGCDVLYSEDLQHGRTFGALRVENPFLEGSR

Download         Length: 405 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9900.21 Da        Isoelectric Point: 4.9534

>AT265370 WP_042441643.1 NZ_CP113083:c3933400-3933146 [Rhodopseudomonas palustris]
MLVSKWGNSLAVRLPKALVDKLDLKEGDELNVVDIVERTLVVEKEDRRKAAVERLSRLRWTLPTDYKFDRDEANERYRDE
SNEP

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References