Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 2242809..2243479 Replicon chromosome
Accession NZ_CP113083
Organism Rhodopseudomonas palustris strain CGA0092

Toxin (Protein)


Gene name vapC Uniprot ID Q6N8B2
Locus tag OR798_RS10270 Protein ID WP_011157547.1
Coordinates 2242809..2243219 (-) Length 137 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag OR798_RS10275 Protein ID WP_011157548.1
Coordinates 2243216..2243479 (-) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OR798_RS10255 (OR798_10255) 2239198..2239524 + 327 WP_011157544.1 hypothetical protein -
OR798_RS10260 (OR798_10260) 2239691..2241481 + 1791 WP_011157545.1 sulfatase-like hydrolase/transferase -
OR798_RS10265 (OR798_10265) 2241517..2242554 + 1038 WP_042441504.1 transporter -
OR798_RS10270 (OR798_10270) 2242809..2243219 - 411 WP_011157547.1 type II toxin-antitoxin system VapC family toxin Toxin
OR798_RS10275 (OR798_10275) 2243216..2243479 - 264 WP_011157548.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
OR798_RS10280 (OR798_10280) 2243660..2244085 + 426 WP_011157549.1 cupin domain-containing protein -
OR798_RS10285 (OR798_10285) 2244182..2245351 - 1170 WP_011157550.1 DUF2865 domain-containing protein -
OR798_RS10290 (OR798_10290) 2245537..2245845 - 309 WP_011157551.1 hypothetical protein -
OR798_RS10295 (OR798_10295) 2246246..2247637 + 1392 WP_011157552.1 cysteine--tRNA ligase -
OR798_RS10300 (OR798_10300) 2247634..2248170 + 537 WP_147408398.1 hypothetical protein -
OR798_RS10305 (OR798_10305) 2248167..2248298 + 132 WP_011157553.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-124)

Antitoxin

SpoVT-AbrB domain

(9-58)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 15136.48 Da        Isoelectric Point: 5.6802

>T265369 WP_011157547.1 NZ_CP113083:c2243219-2242809 [Rhodopseudomonas palustris]
MSGWMLDTNVASHVIRGDRREIIERLVALPISDVVISSITEGELLYGLAKRGYPTALSERVREFLLRVDVLPWDHEVTKT
YADLRAVCEAKGVTLSPLDMMIAAHAAATNATLVTRDKAFSRVPSPLRIEDWAEMS

Download         Length: 411 bp

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9888.91 Da        Isoelectric Point: 4.7969

>AT265369 WP_011157548.1 NZ_CP113083:c2243479-2243216 [Rhodopseudomonas palustris]
VTSRTAKIFTTGRSQAVRLPAEFRFEGSEVFVRRDPRTGDVILSRKPDSWDGLLQLHQSADVPDDFLGPSDRSQLPQDRD
PFEGWTE

Download         Length: 264 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB Q6N8B2

Antitoxin

Source ID Structure

References