Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 449601..450254 Replicon chromosome
Accession NZ_CP113080
Organism Acinetobacter baumannii strain AB5075-T

Toxin (Protein)


Gene name cptA Uniprot ID B0V6V2
Locus tag OSV62_RS02180 Protein ID WP_000931890.1
Coordinates 449865..450254 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag OSV62_RS02175 Protein ID WP_001288210.1
Coordinates 449601..449858 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OSV62_RS02155 (OSV62_02155) 445117..446124 + 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -
OSV62_RS02160 (OSV62_02160) 446143..446520 + 378 WP_001216380.1 50S ribosomal protein L17 -
OSV62_RS02165 (OSV62_02165) 446701..448191 + 1491 WP_000415133.1 NAD(P)/FAD-dependent oxidoreductase -
OSV62_RS02170 (OSV62_02170) 448241..449413 - 1173 WP_001190546.1 acyl-CoA dehydrogenase family protein -
OSV62_RS02175 (OSV62_02175) 449601..449858 + 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
OSV62_RS02180 (OSV62_02180) 449865..450254 + 390 WP_000931890.1 membrane protein Toxin
OSV62_RS02185 (OSV62_02185) 451024..452109 + 1086 WP_000049106.1 hypothetical protein -
OSV62_RS02190 (OSV62_02190) 452187..452753 + 567 WP_000651536.1 rhombosortase -
OSV62_RS02195 (OSV62_02195) 452941..455136 + 2196 WP_001158905.1 TRAP transporter large permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15649.98 Da        Isoelectric Point: 10.4623

>T265367 WP_000931890.1 NZ_CP113080:449865-450254 [Acinetobacter baumannii]
MLNHLNFKLKYSRFSIIFQFFIGLSLAILFYQLMPLLWWLVVISLLFISFIFFLKRPQLAKIAYLDKKLWSLAYHSQNTI
SRVKILKIIDYQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Download         Length: 390 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT265367 WP_001288210.1 NZ_CP113080:449601-449858 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0J1A4U0

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References