Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 1571544..1572197 Replicon chromosome
Accession NZ_CP113078
Organism Acinetobacter baumannii strain AB5075

Toxin (Protein)


Gene name cptA Uniprot ID B0V6V2
Locus tag OSV63_RS07840 Protein ID WP_000931890.1
Coordinates 1571544..1571933 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag OSV63_RS07845 Protein ID WP_001288210.1
Coordinates 1571940..1572197 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OSV63_RS07825 (OSV63_07825) 1566662..1568857 - 2196 WP_001158905.1 TRAP transporter large permease subunit -
OSV63_RS07830 (OSV63_07830) 1569045..1569611 - 567 WP_000651536.1 rhombosortase -
OSV63_RS07835 (OSV63_07835) 1569689..1570774 - 1086 WP_000049106.1 hypothetical protein -
OSV63_RS07840 (OSV63_07840) 1571544..1571933 - 390 WP_000931890.1 membrane protein Toxin
OSV63_RS07845 (OSV63_07845) 1571940..1572197 - 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
OSV63_RS07850 (OSV63_07850) 1572385..1573557 + 1173 WP_001190546.1 acyl-CoA dehydrogenase family protein -
OSV63_RS07855 (OSV63_07855) 1573607..1575097 - 1491 WP_000415133.1 NAD(P)/FAD-dependent oxidoreductase -
OSV63_RS07860 (OSV63_07860) 1575278..1575655 - 378 WP_001216380.1 50S ribosomal protein L17 -
OSV63_RS07865 (OSV63_07865) 1575674..1576681 - 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15649.98 Da        Isoelectric Point: 10.4623

>T265365 WP_000931890.1 NZ_CP113078:c1571933-1571544 [Acinetobacter baumannii]
MLNHLNFKLKYSRFSIIFQFFIGLSLAILFYQLMPLLWWLVVISLLFISFIFFLKRPQLAKIAYLDKKLWSLAYHSQNTI
SRVKILKIIDYQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Download         Length: 390 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT265365 WP_001288210.1 NZ_CP113078:c1572197-1571940 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0J1A4U0

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References