Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 470607..471260 Replicon chromosome
Accession NZ_CP113077
Organism Acinetobacter baumannii strain 86II/2C

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag OSV60_RS02295 Protein ID WP_025469989.1
Coordinates 470871..471260 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag OSV60_RS02290 Protein ID WP_001288210.1
Coordinates 470607..470864 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OSV60_RS02270 (OSV60_02270) 466122..467129 + 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -
OSV60_RS02275 (OSV60_02275) 467148..467525 + 378 WP_001216380.1 50S ribosomal protein L17 -
OSV60_RS02280 (OSV60_02280) 467707..469197 + 1491 WP_000415127.1 NAD(P)/FAD-dependent oxidoreductase -
OSV60_RS02285 (OSV60_02285) 469247..470419 - 1173 WP_004839681.1 acyl-CoA dehydrogenase family protein -
OSV60_RS02290 (OSV60_02290) 470607..470864 + 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
OSV60_RS02295 (OSV60_02295) 470871..471260 + 390 WP_025469989.1 membrane protein Toxin
OSV60_RS02300 (OSV60_02300) 472030..473115 + 1086 WP_000049106.1 hypothetical protein -
OSV60_RS02305 (OSV60_02305) 473193..473759 + 567 WP_000651536.1 rhombosortase -
OSV60_RS02310 (OSV60_02310) 473947..476142 + 2196 WP_001158905.1 TRAP transporter large permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15603.93 Da        Isoelectric Point: 10.3513

>T265364 WP_025469989.1 NZ_CP113077:470871-471260 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLVQIAYLDKKLWSLAYHSQNTI
SRVKILKIIDCQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Download         Length: 390 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT265364 WP_001288210.1 NZ_CP113077:470607-470864 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References