Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 449971..450624 Replicon chromosome
Accession NZ_CP113072
Organism Acinetobacter baumannii strain A118 DeltaH0N27_10820-30::kan

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag OSH16_RS02165 Protein ID WP_168726711.1
Coordinates 450235..450624 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag OSH16_RS02160 Protein ID WP_001288210.1
Coordinates 449971..450228 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OSH16_RS02140 (OSH16_02140) 445486..446493 + 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -
OSH16_RS02145 (OSH16_02145) 446512..446889 + 378 WP_001216380.1 50S ribosomal protein L17 -
OSH16_RS02150 (OSH16_02150) 447071..448561 + 1491 WP_000415133.1 NAD(P)/FAD-dependent oxidoreductase -
OSH16_RS02155 (OSH16_02155) 448611..449783 - 1173 WP_032061191.1 acyl-CoA dehydrogenase family protein -
OSH16_RS02160 (OSH16_02160) 449971..450228 + 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
OSH16_RS02165 (OSH16_02165) 450235..450624 + 390 WP_168726711.1 hypothetical protein Toxin
OSH16_RS02170 (OSH16_02170) 451394..452479 + 1086 WP_000049106.1 hypothetical protein -
OSH16_RS02175 (OSH16_02175) 452557..453123 + 567 WP_000651536.1 rhombosortase -
OSH16_RS02180 (OSH16_02180) 453311..455506 + 2196 WP_001158905.1 TRAP transporter large permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15736.07 Da        Isoelectric Point: 10.3599

>T265356 WP_168726711.1 NZ_CP113072:450235-450624 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAILFYQLMPLLWWLVVISLLFISFIFFLKRPQLAKIAYLDKKLWSLAYHSQNTI
SRVKILKIIDYQIFIVIYFEDHKTLTSIIWFDQMSLVEWKKLKTLEKLY

Download         Length: 390 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT265356 WP_001288210.1 NZ_CP113072:449971-450228 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References