Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 3300976..3301629 Replicon chromosome
Accession NZ_CP113071
Organism Acinetobacter baumannii strain A118 DeltaH0N27_10830::kan

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag OSH14_RS15415 Protein ID WP_168726711.1
Coordinates 3300976..3301365 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag OSH14_RS15420 Protein ID WP_001288210.1
Coordinates 3301372..3301629 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OSH14_RS15400 (OSH14_15400) 3296094..3298289 - 2196 WP_001158905.1 TRAP transporter large permease subunit -
OSH14_RS15405 (OSH14_15405) 3298477..3299043 - 567 WP_000651536.1 rhombosortase -
OSH14_RS15410 (OSH14_15410) 3299121..3300206 - 1086 WP_000049106.1 hypothetical protein -
OSH14_RS15415 (OSH14_15415) 3300976..3301365 - 390 WP_168726711.1 hypothetical protein Toxin
OSH14_RS15420 (OSH14_15420) 3301372..3301629 - 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
OSH14_RS15425 (OSH14_15425) 3301817..3302989 + 1173 WP_032061191.1 acyl-CoA dehydrogenase family protein -
OSH14_RS15430 (OSH14_15430) 3303039..3304529 - 1491 WP_000415133.1 NAD(P)/FAD-dependent oxidoreductase -
OSH14_RS15435 (OSH14_15435) 3304711..3305088 - 378 WP_001216380.1 50S ribosomal protein L17 -
OSH14_RS15440 (OSH14_15440) 3305107..3306114 - 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15736.07 Da        Isoelectric Point: 10.3599

>T265355 WP_168726711.1 NZ_CP113071:c3301365-3300976 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAILFYQLMPLLWWLVVISLLFISFIFFLKRPQLAKIAYLDKKLWSLAYHSQNTI
SRVKILKIIDYQIFIVIYFEDHKTLTSIIWFDQMSLVEWKKLKTLEKLY

Download         Length: 390 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT265355 WP_001288210.1 NZ_CP113071:c3301629-3301372 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References