Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type IV Classification (family/domain) cptAB/-
Location 3301523..3302176 Replicon chromosome
Accession NZ_CP113070
Organism Acinetobacter baumannii strain A118 DeltaH0N27_10825::kan

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag OSH13_RS15410 Protein ID WP_168726711.1
Coordinates 3301523..3301912 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag OSH13_RS15415 Protein ID WP_001288210.1
Coordinates 3301919..3302176 (-) Length 86 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OSH13_RS15395 (OSH13_15395) 3296641..3298836 - 2196 WP_001158905.1 TRAP transporter large permease subunit -
OSH13_RS15400 (OSH13_15400) 3299024..3299590 - 567 WP_000651536.1 rhombosortase -
OSH13_RS15405 (OSH13_15405) 3299668..3300753 - 1086 WP_000049106.1 hypothetical protein -
OSH13_RS15410 (OSH13_15410) 3301523..3301912 - 390 WP_168726711.1 hypothetical protein Toxin
OSH13_RS15415 (OSH13_15415) 3301919..3302176 - 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
OSH13_RS15420 (OSH13_15420) 3302364..3303536 + 1173 WP_032061191.1 acyl-CoA dehydrogenase family protein -
OSH13_RS15425 (OSH13_15425) 3303586..3305076 - 1491 WP_000415133.1 NAD(P)/FAD-dependent oxidoreductase -
OSH13_RS15430 (OSH13_15430) 3305258..3305635 - 378 WP_001216380.1 50S ribosomal protein L17 -
OSH13_RS15435 (OSH13_15435) 3305654..3306661 - 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

(10-82)


Sequences


Toxin        


Download         Length: 130 a.a.        Molecular weight: 15736.07 Da        Isoelectric Point: 10.3599

>T265353 WP_168726711.1 NZ_CP113070:c3301912-3301523 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAILFYQLMPLLWWLVVISLLFISFIFFLKRPQLAKIAYLDKKLWSLAYHSQNTI
SRVKILKIIDYQIFIVIYFEDHKTLTSIIWFDQMSLVEWKKLKTLEKLY

Download         Length: 390 bp


Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT265353 WP_001288210.1 NZ_CP113070:c3302176-3301919 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References