Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 443338..443991 Replicon chromosome
Accession NZ_CP113069
Organism Acinetobacter baumannii strain 29D2

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag OSV61_RS02160 Protein ID WP_065718990.1
Coordinates 443602..443991 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag OSV61_RS02155 Protein ID WP_001288210.1
Coordinates 443338..443595 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OSV61_RS02135 (OSV61_02135) 438853..439860 + 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -
OSV61_RS02140 (OSV61_02140) 439879..440256 + 378 WP_001216380.1 50S ribosomal protein L17 -
OSV61_RS02145 (OSV61_02145) 440438..441928 + 1491 WP_000415133.1 NAD(P)/FAD-dependent oxidoreductase -
OSV61_RS02150 (OSV61_02150) 441978..443150 - 1173 WP_065718991.1 acyl-CoA dehydrogenase family protein -
OSV61_RS02155 (OSV61_02155) 443338..443595 + 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
OSV61_RS02160 (OSV61_02160) 443602..443991 + 390 WP_065718990.1 hypothetical protein Toxin
OSV61_RS02165 (OSV61_02165) 444761..445846 + 1086 WP_000049106.1 hypothetical protein -
OSV61_RS02170 (OSV61_02170) 445924..446490 + 567 WP_000651536.1 rhombosortase -
OSV61_RS02175 (OSV61_02175) 446678..448873 + 2196 WP_065718989.1 TRAP transporter large permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15637.93 Da        Isoelectric Point: 10.4623

>T265351 WP_065718990.1 NZ_CP113069:443602-443991 [Acinetobacter baumannii]
MLNHLNFKLKYSRFSIIFQFFIGLSLAILFYQLMPLLWWLVVISLLFISFIFFLKRPQLAKIAYLDKKLWSLAYHSQNTI
SRVKILKITDYQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Download         Length: 390 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT265351 WP_001288210.1 NZ_CP113069:443338-443595 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References