Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) TscAT/-
Location 428050..428576 Replicon chromosome
Accession NZ_CP113051
Organism Staphylococcus aureus strain Viktor

Toxin (Protein)


Gene name TscT Uniprot ID -
Locus tag OS088_RS02190 Protein ID WP_267814573.1
Coordinates 428256..428576 (+) Length 107 a.a.

Antitoxin (Protein)


Gene name TscA Uniprot ID -
Locus tag OS088_RS02185 Protein ID WP_267814571.1
Coordinates 428050..428253 (+) Length 68 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OS088_RS02155 (424201) 424201..425223 - 1023 Protein_411 site-specific integrase -
OS088_RS02160 (425265) 425265..426626 - 1362 WP_267814566.1 SAP domain-containing protein -
OS088_RS02165 (426653) 426653..427226 - 574 Protein_413 helix-turn-helix transcriptional regulator -
OS088_RS02170 (427398) 427398..427619 + 222 WP_000560872.1 helix-turn-helix transcriptional regulator -
OS088_RS02175 (427620) 427620..427892 + 273 WP_000124597.1 helix-turn-helix domain-containing protein -
OS088_RS02180 (427904) 427904..428050 + 147 WP_000784885.1 hypothetical protein -
OS088_RS02185 (428050) 428050..428253 + 204 WP_267814571.1 pathogenicity island protein Antitoxin
OS088_RS02190 (428256) 428256..428576 + 321 WP_267814573.1 DUF1474 family protein Toxin
OS088_RS02195 (428643) 428643..429512 + 870 WP_077517454.1 primase alpha helix C-terminal domain-containing protein -
OS088_RS02200 (429526) 429526..431237 + 1712 Protein_420 DUF927 domain-containing protein -
OS088_RS02205 (431567) 431567..431947 + 381 WP_000356930.1 hypothetical protein -
OS088_RS02210 (431944) 431944..432585 + 642 WP_064132047.1 pathogenicity island protein -
OS088_RS02215 (432932) 432932..433273 + 342 WP_001161492.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 403937..435587 31650


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Protein of unknown function DUF1474

(1-89)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12493.16 Da        Isoelectric Point: 4.7203

>T265327 WP_267814573.1 NZ_CP113051:428256-428576 [Staphylococcus aureus]
MNWEIKDLMCDIEVIKEKINDVAIKHGWFVEDKFVKNELETKQEHINFSASYLEHRIQNEHTVELLQVYLKEFGELIQKF
HEIEKASSDGTLATESDDAKKLKITE

Download         Length: 321 bp

Antitoxin


Download         Length: 68 a.a.        Molecular weight: 7995.06 Da        Isoelectric Point: 4.4976

>AT265327 WP_267814571.1 NZ_CP113051:428050-428253 [Staphylococcus aureus]
MNKKEVIEHVVYQLELSIMNNFESNEHTEYVDGIEVVSEISREKHLELIMKWCAQELKNNFQLEKGE

Download         Length: 204 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References