Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/COG3657-dnstrm_HI1420
Location 300683..301279 Replicon chromosome
Accession NZ_CP112980
Organism Enterobacter hormaechei subsp. xiangfangensis strain CNCI 7

Toxin (Protein)


Gene name PumA Uniprot ID A0A837F9W8
Locus tag MTX27_RS01450 Protein ID WP_023315213.1
Coordinates 300977..301279 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag MTX27_RS01445 Protein ID WP_032610152.1
Coordinates 300683..300970 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MTX27_RS01440 (MTX27_01440) 299055..300686 + 1632 WP_003860350.1 Na/Pi cotransporter family protein -
MTX27_RS01445 (MTX27_01445) 300683..300970 - 288 WP_032610152.1 putative addiction module antidote protein Antitoxin
MTX27_RS01450 (MTX27_01450) 300977..301279 - 303 WP_023315213.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
MTX27_RS01455 (MTX27_01455) 301477..302349 + 873 WP_003860347.1 23S rRNA pseudouridine(2604) synthase RluF -
MTX27_RS01460 (MTX27_01460) 302350..302622 - 273 WP_003860346.1 DUF3811 domain-containing protein -
MTX27_RS01465 (MTX27_01465) 302673..303617 - 945 WP_032608239.1 ketopantoate/pantoate/pantothenate transporter PanS -
MTX27_RS01470 (MTX27_01470) 303711..305060 - 1350 WP_100154725.1 lysine-sensitive aspartokinase 3 -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-93)

Antitoxin

Uncharacterized protein HI1420

(3-90)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11427.21 Da        Isoelectric Point: 10.1042

>T264970 WP_023315213.1 NZ_CP112980:c301279-300977 [Enterobacter hormaechei subsp. xiangfangensis]
MKEIVQTESFRRWEQNLKDRRAKTIIASRLFRLANGLAGDIRPVGEGISELRIHFGPGYRVYFKDQGNCIIVLLCGGDKS
SQARDILMAKMLSNVSQWQE

Download         Length: 303 bp

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10072.60 Da        Isoelectric Point: 5.7807

>AT264970 WP_032610152.1 NZ_CP112980:c300970-300683 [Enterobacter hormaechei subsp. xiangfangensis]
MHKLTPYDPANALVDDEEIAVFMADALETGDSAYIAKALGVIARAKGMSTISLQTGLSREQLYRSFSDKGNPTLKTTLAV
MKALGLGLTIKPSGD

Download         Length: 288 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A837F9W8

Antitoxin

Source ID Structure

References