264964

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-yefM/Txe-RelB
Location 124492..124999 Replicon chromosome
Accession NZ_CP112971
Organism Rickettsia conorii subsp. heilongjiangensis strain B8

Toxin (Protein)


Gene name relB Uniprot ID -
Locus tag OSR38_RS00665 Protein ID WP_267185184.1
Coordinates 124492..124755 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID G4KM09
Locus tag OSR38_RS00670 Protein ID WP_014013838.1
Coordinates 124748..124999 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OSR38_RS00640 (OSR38_00640) 119997..120179 + 183 WP_267185181.1 hypothetical protein -
OSR38_RS00645 (OSR38_00645) 120302..120925 + 624 WP_267185182.1 hypothetical protein -
OSR38_RS00650 (OSR38_00650) 121029..122423 - 1395 WP_014120498.1 lipid IV(A) 3-deoxy-D-manno-octulosonic acid transferase -
OSR38_RS00655 (OSR38_00655) 122420..123076 - 657 WP_267185183.1 lysophospholipid acyltransferase family protein -
OSR38_RS00660 (OSR38_00660) 123227..124432 - 1206 WP_014013836.1 pyridoxal phosphate-dependent aminotransferase -
OSR38_RS00665 (OSR38_00665) 124492..124755 - 264 WP_267185184.1 Txe/YoeB family addiction module toxin Toxin
OSR38_RS00670 (OSR38_00670) 124748..124999 - 252 WP_014013838.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
OSR38_RS00675 (OSR38_00675) 125139..126143 + 1005 WP_267185185.1 methyltransferase domain-containing protein -
OSR38_RS00680 (OSR38_00680) 126148..126903 + 756 WP_014013840.1 VacJ family lipoprotein -
OSR38_RS00685 (OSR38_00685) 126923..127522 + 600 WP_267185186.1 phospholipid-binding protein MlaC -
OSR38_RS00690 (OSR38_00690) 127746..128033 + 288 WP_045805280.1 ribose-phosphate pyrophosphokinase-like domain-containing protein -
OSR38_RS00695 (OSR38_00695) 128263..128610 + 348 WP_267185525.1 phosphoribosyltransferase family protein -
OSR38_RS00700 (OSR38_00700) 128744..129811 + 1068 WP_014013842.1 alanine racemase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(6-85)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10580.35 Da        Isoelectric Point: 9.8255

>T264964 WP_267185184.1 NZ_CP112971:c124755-124492 [Rickettsia conorii subsp. heilongjiangensis]
MIEIEWTLEAAEDLVYWKKYDIKKYERIKLLIKNIQEASFTGIGKPESLKHILSGLWSRRINHEHRLIYSVNTKQIIIYN
CRFHYKN

Download         Length: 264 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9537.81 Da        Isoelectric Point: 9.4884

>AT264964 WP_014013838.1 NZ_CP112971:c124999-124748 [Rickettsia conorii subsp. heilongjiangensis]
MNSISGTSFRKNLSSVLNTVENDHVPYLIKRKNHKNIILLTEEEYESTKETLYLLSNLANANRIKKSIEQAKRGEFAKVN
LDD

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A6H3RZ38

References