Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/upstrm_HI1419-dnstrm_HI1420 |
Location | 2259309..2259910 | Replicon | chromosome |
Accession | NZ_CP112897 | ||
Organism | Pasteurella multocida strain PF19 |
Toxin (Protein)
Gene name | relE | Uniprot ID | - |
Locus tag | OR617_RS11010 | Protein ID | WP_078819687.1 |
Coordinates | 2259309..2259623 (+) | Length | 105 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | - |
Locus tag | OR617_RS11015 | Protein ID | WP_078819686.1 |
Coordinates | 2259620..2259910 (+) | Length | 97 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
OR617_RS10955 (OR617_10955) | 2254899..2255186 | - | 288 | WP_014391452.1 | hypothetical protein | - |
OR617_RS10960 (OR617_10960) | 2255199..2255435 | - | 237 | WP_075271355.1 | hypothetical protein | - |
OR617_RS10965 (OR617_10965) | 2255407..2255706 | - | 300 | WP_078802174.1 | hypothetical protein | - |
OR617_RS10970 (OR617_10970) | 2255854..2256084 | + | 231 | WP_223251317.1 | hypothetical protein | - |
OR617_RS10975 (OR617_10975) | 2256146..2256802 | - | 657 | WP_225529682.1 | KilA-N domain-containing protein | - |
OR617_RS10980 (OR617_10980) | 2257052..2257420 | - | 369 | Protein_2116 | Bro-N domain-containing protein | - |
OR617_RS10985 (OR617_10985) | 2257784..2257978 | + | 195 | WP_014391459.1 | hypothetical protein | - |
OR617_RS10990 (OR617_10990) | 2257959..2258129 | - | 171 | WP_225529669.1 | hypothetical protein | - |
OR617_RS10995 (OR617_10995) | 2258142..2258372 | - | 231 | WP_078737821.1 | hypothetical protein | - |
OR617_RS11000 (OR617_11000) | 2258614..2258823 | - | 210 | WP_005756656.1 | hypothetical protein | - |
OR617_RS11005 (OR617_11005) | 2258836..2259003 | + | 168 | WP_005756653.1 | DUF1508 domain-containing protein | - |
OR617_RS11010 (OR617_11010) | 2259309..2259623 | + | 315 | WP_078819687.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
OR617_RS11015 (OR617_11015) | 2259620..2259910 | + | 291 | WP_078819686.1 | putative addiction module antidote protein | Antitoxin |
OR617_RS11020 (OR617_11020) | 2259936..2260340 | - | 405 | WP_146024473.1 | hypothetical protein | - |
OR617_RS11025 (OR617_11025) | 2260370..2262214 | - | 1845 | WP_071523830.1 | DEAD/DEAH box helicase family protein | - |
OR617_RS11030 (OR617_11030) | 2262425..2263108 | - | 684 | WP_099821842.1 | S24 family peptidase | - |
OR617_RS11035 (OR617_11035) | 2263233..2263433 | + | 201 | WP_099821841.1 | YdaS family helix-turn-helix protein | - |
OR617_RS11040 (OR617_11040) | 2263482..2263931 | + | 450 | WP_099821840.1 | YmfL family putative regulatory protein | - |
OR617_RS11045 (OR617_11045) | 2263989..2264672 | + | 684 | WP_014390721.1 | phage antirepressor KilAC domain-containing protein | - |
OR617_RS11050 (OR617_11050) | 2264669..2264884 | + | 216 | WP_075271368.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Prophage | - | - | 2246833..2294989 | 48156 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 105 a.a. Molecular weight: 11763.65 Da Isoelectric Point: 9.5553
>T264962 WP_078819687.1 NZ_CP112897:2259309-2259623 [Pasteurella multocida]
MLDIIETTVFNKWLKELKDLSAKAAILARISRAKSGNFGDHKSVGDGLYEMRIMKGAGYRVYYAQYKDVTYLLICGGDKS
TQKADIAKAKALWEEIKQKEEINV
MLDIIETTVFNKWLKELKDLSAKAAILARISRAKSGNFGDHKSVGDGLYEMRIMKGAGYRVYYAQYKDVTYLLICGGDKS
TQKADIAKAKALWEEIKQKEEINV
Download Length: 315 bp
Antitoxin
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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