Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) shpAB/BrnT-BrnA
Location 4726109..4726688 Replicon chromosome
Accession NZ_CP112887
Organism Raoultella electrica strain S2-IND-01-C

Toxin (Protein)


Gene name shpA Uniprot ID -
Locus tag OR613_RS22860 Protein ID WP_131049471.1
Coordinates 4726401..4726688 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name shpB Uniprot ID -
Locus tag OR613_RS22855 Protein ID WP_131049472.1
Coordinates 4726109..4726414 (-) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OR613_RS22845 (OR613_22840) 4722148..4725414 + 3267 WP_131049474.1 HsdR family type I site-specific deoxyribonuclease -
OR613_RS22850 (OR613_22845) 4725638..4725973 + 336 WP_131049473.1 endoribonuclease SymE -
OR613_RS22855 (OR613_22850) 4726109..4726414 - 306 WP_131049472.1 BrnA antitoxin family protein Antitoxin
OR613_RS22860 (OR613_22855) 4726401..4726688 - 288 WP_131049471.1 BrnT family toxin Toxin
OR613_RS22865 (OR613_22860) 4727063..4727506 - 444 WP_131049470.1 FosA family fosfomycin resistance glutathione transferase -
OR613_RS22870 (OR613_22865) 4727500..4728408 - 909 WP_131049469.1 LysR family transcriptional regulator -
OR613_RS22875 (OR613_22870) 4728496..4729278 + 783 WP_131049468.1 NAD(P)H-dependent oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 4714598..4726688 12090


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(7-88)

Antitoxin

BrnA antitoxin of type II toxin-antitoxin system

(37-93)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11135.61 Da        Isoelectric Point: 8.5787

>T264953 WP_131049471.1 NZ_CP112887:c4726688-4726401 [Raoultella electrica]
MPMEFEWDANKAASNLRKHGIRFEEAVLVFDDPQHLSRQDRYQNGEYRWQTLGLVHGIIVILVAHSVRFESGTEVIRIIS
ARKADKKERSRYEHG

Download         Length: 288 bp

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 11651.19 Da        Isoelectric Point: 9.7962

>AT264953 WP_131049472.1 NZ_CP112887:c4726414-4726109 [Raoultella electrica]
MNMVKHKRDNPAALTAQREDELKALAKKSDDDIDYSDIPSSDDEQWSEAVRGKFYRPLKTQASVRIDADVMAWLKRPGKG
YQTRLNAILREAMIREQNKKS

Download         Length: 306 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References