264952

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yfjZ-ypjF/CbtA-CbeA
Location 4343553..4344196 Replicon chromosome
Accession NZ_CP112887
Organism Raoultella electrica strain S2-IND-01-C

Toxin (Protein)


Gene name ypjF Uniprot ID -
Locus tag OR613_RS21115 Protein ID WP_271207263.1
Coordinates 4343891..4344196 (+) Length 102 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag OR613_RS21110 Protein ID WP_165457187.1
Coordinates 4343553..4343870 (+) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OR613_RS21095 (OR613_21095) 4338971..4341649 - 2679 WP_131049958.1 DNA repair protein -
OR613_RS21100 (OR613_21100) 4342574..4342990 + 417 Protein_4147 DUF932 domain-containing protein -
OR613_RS21105 (OR613_21105) 4343061..4343531 + 471 WP_131049960.1 DNA repair protein RadC -
OR613_RS21110 (OR613_21110) 4343553..4343870 + 318 WP_165457187.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
OR613_RS21115 (OR613_21115) 4343891..4344196 + 306 WP_271207263.1 TA system toxin CbtA family protein Toxin
OR613_RS21120 (OR613_21120) 4344230..4345768 - 1539 WP_004181747.1 IS66 family transposase -
OR613_RS21125 (OR613_21125) 4345818..4346126 - 309 WP_271207637.1 IS66 family insertion sequence element accessory protein TnpB -
OR613_RS21130 (OR613_21130) 4346123..4347661 - 1539 WP_059593943.1 IS66-like element ISKpn24 family transposase -
OR613_RS21135 (OR613_21135) 4347710..4348057 - 348 WP_000612626.1 IS66 family insertion sequence element accessory protein TnpB -
OR613_RS21140 (OR613_21140) 4348054..4348458 - 405 WP_000839182.1 transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 4328131..4350840 22709


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-100)

Antitoxin

Antitoxin CbeA

(4-104)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11401.13 Da        Isoelectric Point: 6.7155

>T264952 WP_271207263.1 NZ_CP112887:4343891-4344196 [Raoultella electrica]
MKTLSATISRAVKPCLSPVAVWQMLLTRLLEQHYGLTLNDTPFSDETVIKEHIDAGITLADAANFLVDKYELVRIDRRGF
SSQGQEPYLTVTDILHARKAW

Download         Length: 306 bp

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 11872.49 Da        Isoelectric Point: 6.7388

>AT264952 WP_165457187.1 NZ_CP112887:4343553-4343870 [Raoultella electrica]
ISAHEWGLKRDIVPRFGARLIQEGNRLHYLADRAGITGKFNDAECLKLDDAFPHFISQMESILTTGEMNPRHAHCVTLYH
NGFTCEADTLGSCGYVYIAIYLTQR

Download         Length: 318 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References