Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ataRT/DUF1778(antitoxin)
Location 2667717..2668468 Replicon chromosome
Accession NZ_CP112887
Organism Raoultella electrica strain S2-IND-01-C

Toxin (Protein)


Gene name ataT Uniprot ID -
Locus tag OR613_RS13050 Protein ID WP_131050355.1
Coordinates 2667986..2668468 (+) Length 161 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag OR613_RS13045 Protein ID WP_100683705.1
Coordinates 2667717..2667995 (+) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OR613_RS13025 (OR613_13030) 2663085..2664185 - 1101 WP_131050358.1 amino acid ABC transporter permease -
OR613_RS13030 (OR613_13035) 2664201..2665379 - 1179 WP_131050357.1 amino acid ABC transporter permease -
OR613_RS13035 (OR613_13040) 2665450..2666475 - 1026 WP_100683707.1 amino acid ABC transporter substrate-binding protein -
OR613_RS13040 (OR613_13045) 2667035..2667637 + 603 WP_131050356.1 DJ-1/PfpI family protein -
OR613_RS13045 (OR613_13050) 2667717..2667995 + 279 WP_100683705.1 DUF1778 domain-containing protein Antitoxin
OR613_RS13050 (OR613_13055) 2667986..2668468 + 483 WP_131050355.1 GNAT family N-acetyltransferase Toxin
OR613_RS13055 (OR613_13060) 2668519..2669055 + 537 WP_131050354.1 dihydrofolate reductase family protein -
OR613_RS13060 (OR613_13065) 2669215..2670006 - 792 WP_131050353.1 tetratricopeptide repeat protein -
OR613_RS13065 (OR613_13070) 2670113..2670559 - 447 Protein_2558 helix-turn-helix domain-containing protein -
OR613_RS13070 (OR613_13075) 2670605..2671096 + 492 Protein_2559 DUF637 domain-containing protein -
OR613_RS13075 (OR613_13080) 2671402..2671905 + 504 WP_131050351.1 Imm70 family immunity protein -
OR613_RS13080 (OR613_13085) 2672166..2672730 + 565 Protein_2561 SOS response-associated peptidase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(46-144)

Antitoxin

Vibrio phage ICP1, Orf50

(10-86)


Sequences

Toxin        


Download         Length: 161 a.a.        Molecular weight: 17650.46 Da        Isoelectric Point: 9.1931

>T264949 WP_131050355.1 NZ_CP112887:2667986-2668468 [Raoultella electrica]
MGMRPPESLTPEHDIAEFCCQDPGLNEWLKKKALKNHSTGISRVYVVCAGNTNRVIAYYCLSSGSVHRNTVPGTFRRNAP
ESVPVIVLGRLAVDVSWAGKGLGAALLKDAIYRTQNIAVQVGVRALLVHALNDEVRDFYTRFGFEPSIVNVLTLLFPIRL

Download         Length: 483 bp

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10740.28 Da        Isoelectric Point: 4.5533

>AT264949 WP_100683705.1 NZ_CP112887:2667717-2667995 [Raoultella electrica]
MKPDIREAPINIRAKTSQRDLIDMAANLVSKSRTDFMLEAACREAQDILLDQRLFLLDDKQFESFIEELDAPMTAERQAR
IDNLMNRKSPWE

Download         Length: 279 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References