Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 817916..818573 Replicon chromosome
Accession NZ_CP112887
Organism Raoultella electrica strain S2-IND-01-C

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag OR613_RS04005 Protein ID WP_100684294.1
Coordinates 818163..818573 (+) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A514ELX1
Locus tag OR613_RS04000 Protein ID WP_004867358.1
Coordinates 817916..818182 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OR613_RS03975 (OR613_03970) 813057..814490 - 1434 WP_131048602.1 6-phospho-beta-glucosidase -
OR613_RS03980 (OR613_03975) 814610..815338 - 729 WP_131048725.1 MurR/RpiR family transcriptional regulator -
OR613_RS03985 (OR613_03980) 815388..815699 + 312 WP_131048603.1 N(4)-acetylcytidine aminohydrolase -
OR613_RS03990 (OR613_03985) 815861..816520 + 660 WP_131048604.1 hemolysin III family protein -
OR613_RS03995 (OR613_03990) 816636..817619 - 984 WP_131048605.1 tRNA-modifying protein YgfZ -
OR613_RS04000 (OR613_03995) 817916..818182 + 267 WP_004867358.1 FAD assembly factor SdhE Antitoxin
OR613_RS04005 (OR613_04000) 818163..818573 + 411 WP_100684294.1 protein YgfX Toxin
OR613_RS04010 (OR613_04005) 818579..819100 - 522 WP_131048606.1 flavodoxin FldB -
OR613_RS04015 (OR613_04010) 819278..820174 + 897 WP_131048607.1 site-specific tyrosine recombinase XerD -
OR613_RS04020 (OR613_04015) 820197..820910 + 714 WP_131048608.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
OR613_RS04025 (OR613_04020) 820916..822649 + 1734 WP_131048609.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 16212.09 Da        Isoelectric Point: 11.5202

>T264941 WP_100684294.1 NZ_CP112887:818163-818573 [Raoultella electrica]
VVLWQSDLRISWRSQWFSLLLHGVVAAIVLLMPWPLSYTPLWLLLLSLVVFDSVRSQRRIHACRGEIKLMTDSRLRWQKA
EWEIVGTPWVINSGMLLRLQDMQTRRRQHLWVAADSMDAREWRDLRRLVLQKPAQD

Download         Length: 411 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10553.05 Da        Isoelectric Point: 4.8432

>AT264941 WP_004867358.1 NZ_CP112887:817916-818182 [Raoultella electrica]
MDITNKARIHWACRRGMRELDISIMPFFEYEYDTLSDEDKQLFIRLLENDDPDLFNWLMNHGEPADAQLQRMVKLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A514ELX1

References