Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 676329..676882 Replicon chromosome
Accession NZ_CP112887
Organism Raoultella electrica strain S2-IND-01-C

Toxin (Protein)


Gene name ccdB Uniprot ID -
Locus tag OR613_RS03285 Protein ID WP_100683472.1
Coordinates 676568..676882 (+) Length 105 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID -
Locus tag OR613_RS03280 Protein ID WP_100683473.1
Coordinates 676329..676565 (+) Length 79 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OR613_RS03260 (OR613_03255) 671781..672359 + 579 WP_131048551.1 TetR/AcrR family transcriptional regulator -
OR613_RS03265 (OR613_03260) 672360..673394 - 1035 WP_242627883.1 iron-containing redox enzyme family protein -
OR613_RS03270 (OR613_03265) 673665..674567 + 903 WP_131048553.1 DMT family transporter -
OR613_RS03275 (OR613_03270) 674609..675766 + 1158 WP_131048554.1 MFS transporter -
OR613_RS03280 (OR613_03275) 676329..676565 + 237 WP_100683473.1 type II toxin-antitoxin system CcdA family antitoxin Antitoxin
OR613_RS03285 (OR613_03280) 676568..676882 + 315 WP_100683472.1 CcdB family protein Toxin
OR613_RS03290 (OR613_03285) 676879..677031 - 153 Protein_644 molybdopterin-guanine dinucleotide biosynthesis protein MobC -
OR613_RS03295 (OR613_03290) 677736..678734 - 999 WP_131048555.1 aldo/keto reductase -
OR613_RS03300 (OR613_03295) 678835..679746 + 912 WP_131048556.1 LysR family transcriptional regulator -
OR613_RS03305 (OR613_03300) 679960..680124 - 165 Protein_647 transposase domain-containing protein -
OR613_RS03310 (OR613_03305) 680368..680853 + 486 WP_131048558.1 MarR family transcriptional regulator -
OR613_RS03315 (OR613_03310) 680882..681727 + 846 WP_131048559.1 GNAT family N-acetyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(2-103)

Antitoxin

Post-segregation antitoxin CcdA

(9-78)


Sequences

Toxin        


Download         Length: 105 a.a.        Molecular weight: 11475.29 Da        Isoelectric Point: 6.4489

>T264940 WP_100683472.1 NZ_CP112887:676568-676882 [Raoultella electrica]
MQFTVYANTGKSTVYPLLLDVTSDIIGQLNRRIVIPLLPVDRYPAGHRPDRLVPFVSLTDGREYAVMTHELASIPVQALG
AVFCDAAQYRSQVKAAIDFLIDGI

Download         Length: 315 bp

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 8929.94 Da        Isoelectric Point: 6.4798

>AT264940 WP_100683473.1 NZ_CP112887:676329-676565 [Raoultella electrica]
MAAKQRSTQSVTMTVERALLARAREAGINLSATLTAALDAELRHHEAKKWQEENREAIEALNRFHDEHGCFSDEYRTF

Download         Length: 237 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References