Detailed information of TA system TA264939

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): rlegTA/AbiEii(toxin)
• Location: 312592..314026
• Replicon: chromosome
• Accession: NZ_CP112881
• Organism: Sneathiella aquimaris strain 216LB-ZA1-12

Toxin (Protein)

• Gene name: rlegT
• Uniprot ID: -
• Locus tag: OIR97_RS01535
• Protein ID: WP_169543968.1
• Coordinates: 313160..314026 (+)
• Length: 289 a.a.

Antitoxin (Protein)

• Gene name: rlegA
• Uniprot ID: -
• Locus tag: OIR97_RS01530
• Protein ID: WP_246201963.1
• Coordinates: 312592..313167 (+)
• Length: 192 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OIR97_RS01510	307978..309774	+	1797	WP_169543965.1	IlvD/Edd family dehydratase	-
OIR97_RS01515	309787..310686	+	900	WP_169543966.1	sugar kinase	-
OIR97_RS01520	310679..311329	+	651	WP_219821629.1	2-dehydro-3-deoxy-6-phosphogalactonate aldolase	-
OIR97_RS01525	311569..312336	+	768	WP_169543967.1	MFS transporter	-
OIR97_RS01530	312592..313167	+	576	WP_246201963.1	type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein	Antitoxin
OIR97_RS01535	313160..314026	+	867	WP_169543968.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	Toxin
OIR97_RS01540	314569..315174	-	606	WP_169543969.1	NAD(P)H-dependent oxidoreductase	-
OIR97_RS01545	315290..316210	+	921	WP_169543970.1	LysR family transcriptional regulator	-
OIR97_RS01550	316694..317479	+	786	WP_169543971.1	fumarylacetoacetate hydrolase family protein	-
OIR97_RS01555	317500..318378	-	879	WP_169543972.1	DMT family transporter	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Nucleotidyl transferase AbiEii toxin, Type IV TA system (38-262)

Antitoxin

• Transcriptional regulator, AbiEi antitoxin (3-41)

Sequences

Toxin

Protein

• Length: 289 a.a.
• Molecular weight: 32267.69 Da
• Isoelectric Point: 4.4568

>T264939 WP_169543968.1 NZ_CP112881:313160-314026 [Sneathiella aquimaris]
MAKQPKDIAASVRQRLLNLAREEQRVFEVVLVAFGLERLIYRLSVSDYRERFVLKGGMLVTLWTTDPGRFTRDVDFLGFG
DDDEGQLKAVFAEILAMDVNDGLTFDSADISASDIREDQVYGGKRLKTTAYLGKIRIPITIDLGFGDTLGDPKFEIEYTS
LLDFEAAKIRAYSPATVIAEKFQAVVDLGVVNGRMKDFYDLWAVPKAKEIPDNDLARALKSTFDRRHTEIPTDRPPGLSE
EFATEPAKVTQWTAYAESTELEDVSLEAVVDEIWERLAPICLAASKLS

Nucleotide

• Length: 867 bp

Antitoxin

Protein

• Length: 192 a.a.
• Molecular weight: 20970.40 Da
• Isoelectric Point: 10.4596

>AT264939 WP_246201963.1 NZ_CP112881:312592-313167 [Sneathiella aquimaris]
MARHPLARPRDLREVGVTGTVIKRAMDDGDIIRIGRGLYQLTGTDIELNASLAEVSKQAPKAIICLMSALSFHGLTDQLP
RKVWIAIGAKDWKPKISYPRTRTVRFREPYLSKGVESFKIGSVDVKIYSAAKSIADAFRNPKLVDRSVAIECLKTALETR
KASPASLANAAENYGVGKLMRPYLEALTSNG

Nucleotide

• Length: 576 bp