Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | /Xre(antitoxin) |
| Location | 290915..292010 | Replicon | chromosome |
| Accession | NZ_CP112881 | ||
| Organism | Sneathiella aquimaris strain 216LB-ZA1-12 | ||
Toxin (Protein)
| Gene name | - | Uniprot ID | - |
| Locus tag | OIR97_RS01415 | Protein ID | WP_169543948.1 |
| Coordinates | 290915..291664 (-) | Length | 250 a.a. |
Antitoxin (Protein)
| Gene name | - | Uniprot ID | - |
| Locus tag | OIR97_RS01420 | Protein ID | WP_169543949.1 |
| Coordinates | 291651..292010 (-) | Length | 120 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| OIR97_RS01390 | 286063..287748 | - | 1686 | WP_169543946.1 | methyl-accepting chemotaxis protein | - |
| OIR97_RS01395 | 288290..288694 | - | 405 | WP_169543947.1 | LysR family transcriptional regulator | - |
| OIR97_RS01400 | 289009..289188 | - | 180 | Protein_275 | IS110 family transposase | - |
| OIR97_RS01405 | 289227..289539 | - | 313 | Protein_276 | IS3 family transposase | - |
| OIR97_RS01410 | 289533..290461 | + | 929 | Protein_277 | IS3 family transposase | - |
| OIR97_RS01415 | 290915..291664 | - | 750 | WP_169543948.1 | RES family NAD+ phosphorylase | Toxin |
| OIR97_RS01420 | 291651..292010 | - | 360 | WP_169543949.1 | MbcA/ParS/Xre antitoxin family protein | Antitoxin |
| OIR97_RS01425 | 292884..294272 | - | 1389 | Protein_280 | mercury(II) reductase | - |
| OIR97_RS01430 | 294311..294541 | - | 231 | WP_169543951.1 | mercury resistance system transport protein MerF | - |
| OIR97_RS01435 | 294547..294831 | - | 285 | WP_169543952.1 | mercury resistance system periplasmic binding protein MerP | - |
| OIR97_RS01440 | 294845..295243 | - | 399 | WP_267177761.1 | mercuric transporter MerT family protein | - |
| OIR97_RS01445 | 295331..295747 | + | 417 | WP_169543953.1 | helix-turn-helix domain-containing protein | - |
| OIR97_RS01450 | 296414..296896 | + | 483 | WP_169543954.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 250 a.a. Molecular weight: 28250.36 Da Isoelectric Point: 4.9343
>T264938 WP_169543948.1 NZ_CP112881:c291664-290915 [Sneathiella aquimaris]
VERSEWKEVLSQAQPETLKGLLWRVVEGQSEIATMELVETLDEQMRLEELLDATKPSCPKTAPDDYLLATPFRYPPLKWG
SRFGAQHEMSIFYGSLLKETAAAELTYYRFVFLEGVEEEFPNPMIRASYDLFSVRFKCEHGLDLTKAPFTASTDTLQHKT
NYQPTQALGSELRAAEIQGITYQSARCPKAGLNIAIFEPAGIISKKPVQMLKCYCEATRSRVVLKLDRTQFVEFPRDLFV
IDGNLPEPA
VERSEWKEVLSQAQPETLKGLLWRVVEGQSEIATMELVETLDEQMRLEELLDATKPSCPKTAPDDYLLATPFRYPPLKWG
SRFGAQHEMSIFYGSLLKETAAAELTYYRFVFLEGVEEEFPNPMIRASYDLFSVRFKCEHGLDLTKAPFTASTDTLQHKT
NYQPTQALGSELRAAEIQGITYQSARCPKAGLNIAIFEPAGIISKKPVQMLKCYCEATRSRVVLKLDRTQFVEFPRDLFV
IDGNLPEPA
Download Length: 750 bp
Antitoxin
Download Length: 120 a.a. Molecular weight: 13086.33 Da Isoelectric Point: 10.5257
>AT264938 WP_169543949.1 NZ_CP112881:c292010-291651 [Sneathiella aquimaris]
MALQQQAIEVDDKAILAKAAKNAASNLGIPLEELAKIIGRDRTAINRGIDPTTKTGELALLFVRCYRALHTLVGGDPKNM
KHWFGTRNKHLNGIPRELIKSVQGLNSVLIYLDGMRGKI
MALQQQAIEVDDKAILAKAAKNAASNLGIPLEELAKIIGRDRTAINRGIDPTTKTGELALLFVRCYRALHTLVGGDPKNM
KHWFGTRNKHLNGIPRELIKSVQGLNSVLIYLDGMRGKI
Download Length: 360 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|