Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PP_4151-4152/excise(antitoxin)
Location 116195..117224 Replicon plasmid pPg_03
Accession NZ_CP112877
Organism Pseudanabaena galeata CCNP1313

Toxin (Protein)


Gene name PP_4152 Uniprot ID -
Locus tag OA858_RS25205 Protein ID WP_281009840.1
Coordinates 116643..117224 (+) Length 194 a.a.

Antitoxin (Protein)


Gene name PP_4151 Uniprot ID -
Locus tag OA858_RS25200 Protein ID WP_281009839.1
Coordinates 116195..116650 (+) Length 152 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OA858_RS25160 (OA858_25155) 111333..111989 + 657 WP_281009831.1 hypothetical protein -
OA858_RS25165 (OA858_25160) 112168..113004 - 837 WP_281009832.1 ThiF family adenylyltransferase -
OA858_RS25170 (OA858_25165) 113004..113693 - 690 WP_281009834.1 Mov34/MPN/PAD-1 family protein -
OA858_RS25175 (OA858_25170) 113690..114397 - 708 WP_281009835.1 hypothetical protein -
OA858_RS25180 (OA858_25175) 114408..115160 - 753 WP_281009836.1 hypothetical protein -
OA858_RS25185 (OA858_25180) 115162..115413 - 252 WP_281009837.1 hypothetical protein -
OA858_RS25190 (OA858_25185) 115410..115607 - 198 WP_144052548.1 hypothetical protein -
OA858_RS25195 (OA858_25190) 115619..115930 - 312 WP_281009838.1 hypothetical protein -
OA858_RS25200 (OA858_25195) 116195..116650 + 456 WP_281009839.1 helix-turn-helix domain-containing protein Antitoxin
OA858_RS25205 (OA858_25200) 116643..117224 + 582 WP_281009840.1 PIN domain-containing protein Toxin
OA858_RS25210 (OA858_25205) 117417..117854 - 438 WP_281009841.1 hypothetical protein -
OA858_RS25215 (OA858_25210) 117965..118372 - 408 WP_281009842.1 single-stranded DNA-binding protein -
OA858_RS25220 (OA858_25215) 118466..119113 - 648 WP_281006125.1 IS630 family transposase -
OA858_RS25225 (OA858_25220) 119026..119430 - 405 WP_281006124.1 IS630 transposase-related protein -
OA858_RS25230 (OA858_25225) 119561..119947 - 387 WP_281009843.1 hypothetical protein -
OA858_RS25235 (OA858_25230) 120041..121201 - 1161 WP_281009844.1 AAA family ATPase -
OA858_RS25240 (OA858_25235) 121325..121870 - 546 WP_281009950.1 VWA domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - katB 1..174751 174751


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(7-114)

Antitoxin

SinI-like, DNA-binding domain

(81-127)


Sequences

Toxin        


Download         Length: 194 a.a.        Molecular weight: 22106.57 Da        Isoelectric Point: 5.2749

>T264934 WP_281009840.1 NZ_CP112877:116643-117224 [Pseudanabaena galeata CCNP1313]
MTSKFTVIYDACVLYSNYLRDILIQLAIADLFRAKWTNLIHDEWIRNLIENRPDLPKEKLNQVKDLMNSQVRDSLVTDFE
QLIPSLTLPDPNDHHILAAAIVAEADVIVTFNLKDFPDLNISQYGITAKHPDDFIADLIGLNPFKVMAAVETCRQRLKKQ
PKTSNEYLEILLKQGLPLSVSMLKELQNNQNTM

Download         Length: 582 bp

Antitoxin


Download         Length: 152 a.a.        Molecular weight: 16784.10 Da        Isoelectric Point: 4.6199

>AT264934 WP_281009839.1 NZ_CP112877:116195-116650 [Pseudanabaena galeata CCNP1313]
MVALTQSLHIPTEEETEISKESSRILASHISDGVCHLKIVEADGSEETATIPAAAYRLFVDILTQMSQGNAVTIIPIHAE
LTTQEAADLINVSRPFLIKQLEEGIIPYHKVGTHRRVRFTDLMEYKTNIDAARNKVLDEIVAISEEIGLYD

Download         Length: 456 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References