Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hipBA/HipA-HipB
Location 45446..47034 Replicon plasmid pPg_02
Accession NZ_CP112876
Organism Pseudanabaena galeata CCNP1313

Toxin (Protein)


Gene name hipA Uniprot ID -
Locus tag OA858_RS23845 Protein ID WP_281009764.1
Coordinates 45691..47034 (+) Length 448 a.a.

Antitoxin (Protein)


Gene name hipB Uniprot ID -
Locus tag OA858_RS23840 Protein ID WP_281009763.1
Coordinates 45446..45697 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OA858_RS23795 (OA858_23795) 40842..41165 - 324 WP_281009756.1 XisI protein -
OA858_RS23800 (OA858_23800) 41135..41569 - 435 Protein_53 XisH family protein -
OA858_RS23805 (OA858_23805) 41770..41994 + 225 WP_281009757.1 DUF433 domain-containing protein -
OA858_RS23810 (OA858_23810) 41991..42329 + 339 WP_281009758.1 DUF5615 family PIN-like protein -
OA858_RS23815 (OA858_23815) 42508..42852 + 345 Protein_56 type II toxin-antitoxin system RelE/ParE family toxin -
OA858_RS23820 (OA858_23820) 42839..43144 + 306 WP_281009759.1 transcriptional regulator -
OA858_RS23825 (OA858_23825) 43231..43428 + 198 WP_281009760.1 hypothetical protein -
OA858_RS23830 (OA858_23830) 43358..44425 + 1068 WP_281009761.1 PDDEXK nuclease domain-containing protein -
OA858_RS23835 (OA858_23835) 44594..45235 - 642 WP_281009762.1 type I restriction endonuclease subunit R -
OA858_RS23840 (OA858_23840) 45446..45697 + 252 WP_281009763.1 helix-turn-helix domain-containing protein Antitoxin
OA858_RS23845 (OA858_23845) 45691..47034 + 1344 WP_281009764.1 type II toxin-antitoxin system HipA family toxin Toxin
OA858_RS23850 (OA858_23850) 47042..49231 + 2190 WP_281009765.1 AAA family ATPase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..216652 216652


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA, N-terminal subdomain 1

(10-109)

Antitoxin

Cro/C1-type helix-turn-helix domain

(10-67)


Sequences

Toxin        


Download         Length: 448 a.a.        Molecular weight: 50894.01 Da        Isoelectric Point: 7.9661

>T264931 WP_281009764.1 NZ_CP112876:45691-47034 [Pseudanabaena galeata CCNP1313]
MVRTRRVNSLNILMNGYLVGTWQNLPSGAMNFQYAEEWLETDGARPISLSMPLRRQPYEGDLVYNFFDNLLPDSREIRAR
IQKRFSISTSQPFDLLTAIGADCVGAIQICHEGISQTIETTQSQPLSTDEVARYLKEYKTTSIGTTQNNNDFRISIAGAQ
EKTALLWHKGKWCRPIGTTPTSHIFKFPIGIIPNDNLNMSDSCENEWLCLQIAKAFGLPTAEAQIQHFNDVKVLVIERFD
RRWSQDRRWLIRLPQEDMCQALGMSPNLKYQNQGGAGISEIMKVLLGAEDANGDREKFFRSQILFWLLAATDGHSKNFSI
YINQGGSYRLTPLYDVISVYPFIKNKSLSKRNAKMSMSLRGEKTNYYNWESIQPRHFISTAKAVNFSEAKASIILEEMLT
NVDDVVAQVNTVLPEDFPTHVSQPILEGMLSLAKRSLNNRAQWIYQP

Download         Length: 1344 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9711.16 Da        Isoelectric Point: 9.6887

>AT264931 WP_281009763.1 NZ_CP112876:45446-45697 [Pseudanabaena galeata CCNP1313]
MLIHSSKELAEYLRDRRKRQKLSQAEIGDRVGIKQATISAFENNPEGTKLETLFKLFSALDLEIQIIPKEEARKPKQGWK
EEW

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References