Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacT-ataR/DUF1778(antitoxin)
Location 4694699..4695495 Replicon chromosome
Accession NZ_CP112874
Organism Pseudanabaena galeata CCNP1313

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag OA858_RS21465 Protein ID WP_281007164.1
Coordinates 4694699..4695208 (-) Length 170 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag OA858_RS21470 Protein ID WP_281007165.1
Coordinates 4695199..4695495 (-) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OA858_RS21435 (OA858_21435) 4690129..4690365 + 237 WP_281007159.1 PQQ-dependent sugar dehydrogenase -
OA858_RS21440 (OA858_21440) 4690623..4690751 - 129 WP_281007160.1 hypothetical protein -
OA858_RS21445 (OA858_21445) 4690850..4690951 - 102 WP_281009444.1 DUF1778 domain-containing protein -
OA858_RS21450 (OA858_21450) 4691289..4692833 - 1545 WP_281007161.1 DNA (cytosine-5-)-methyltransferase -
OA858_RS21455 (OA858_21455) 4692857..4693690 - 834 WP_281007162.1 TdeIII family type II restriction endonuclease -
OA858_RS21460 (OA858_21460) 4693894..4694502 + 609 WP_281007163.1 hypothetical protein -
OA858_RS21465 (OA858_21465) 4694699..4695208 - 510 WP_281007164.1 GNAT family N-acetyltransferase Toxin
OA858_RS21470 (OA858_21470) 4695199..4695495 - 297 WP_281007165.1 DUF1778 domain-containing protein Antitoxin
OA858_RS21475 (OA858_21475) 4695744..4696001 - 258 WP_281007166.1 DUF86 domain-containing protein -
OA858_RS21480 (OA858_21480) 4695991..4696314 - 324 WP_281007167.1 nucleotidyltransferase family protein -
OA858_RS21485 (OA858_21485) 4696427..4697623 - 1197 WP_281007168.1 hypothetical protein -
OA858_RS21490 (OA858_21490) 4697658..4697861 - 204 WP_281007169.1 DUF2281 domain-containing protein -
OA858_RS21495 (OA858_21495) 4697876..4699732 - 1857 WP_281007170.1 N-6 DNA methylase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(48-148)

Antitoxin

Vibrio phage ICP1, Orf50

(8-98)


Sequences

Toxin        


Download         Length: 170 a.a.        Molecular weight: 18546.50 Da        Isoelectric Point: 9.1820

>T264929 WP_281007164.1 NZ_CP112874:c4695208-4694699 [Pseudanabaena galeata CCNP1313]
VGISLDNLRSPEKLNSSHQIKGFDSGNSQLDDWLKNRAIKNEMEGASRTYVLCADNVVIGFYCLANGSVVQSVATGKVRR
NMPDPIPVMVLGRLAIDRSWQGKGLGRALLRDAILRTLQASEIAGIRAILVHAISENAKVFYEKCGFTASPIDEMTLMIR
IKDAIAIFQ

Download         Length: 510 bp

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 11323.76 Da        Isoelectric Point: 5.1212

>AT264929 WP_281007165.1 NZ_CP112874:c4695495-4695199 [Pseudanabaena galeata CCNP1313]
MSTLIDNTTSSQNRDVTINIRVKQEKRNIIDRAAEVQGKTRSEFMLESAYQKAQDVLLDWAFFDLDSSKYQEFTALLDGV
PQPNQKLQKLLTTKSPWE

Download         Length: 297 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References