Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 3475138..3475728 Replicon chromosome
Accession NZ_CP112874
Organism Pseudanabaena galeata CCNP1313

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag OA858_RS15780 Protein ID WP_281009425.1
Coordinates 3475435..3475728 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag OA858_RS15775 Protein ID WP_281006155.1
Coordinates 3475138..3475431 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OA858_RS15755 (OA858_15750) 3472381..3473211 - 831 WP_281009424.1 Rpn family recombination-promoting nuclease/putative transposase -
OA858_RS15760 (OA858_15755) 3473233..3474375 - 1143 WP_281005925.1 transposase -
OA858_RS15765 (OA858_15760) 3474462..3474575 - 114 Protein_3124 PD-(D/E)XK nuclease family transposase -
OA858_RS15770 (OA858_15765) 3474951..3475145 + 195 WP_281006154.1 DUF433 domain-containing protein -
OA858_RS15775 (OA858_15770) 3475138..3475431 - 294 WP_281006155.1 putative addiction module antidote protein Antitoxin
OA858_RS15780 (OA858_15775) 3475435..3475728 - 294 WP_281009425.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OA858_RS15785 (OA858_15780) 3475949..3476362 + 414 WP_281006156.1 hypothetical protein -
OA858_RS15790 (OA858_15785) 3476408..3478294 - 1887 WP_281006157.1 AAA family ATPase -
OA858_RS15795 (OA858_15790) 3478425..3479408 + 984 WP_281006158.1 IS30 family transposase -
OA858_RS15800 (OA858_15795) 3479382..3479798 - 417 WP_281006159.1 hypothetical protein -
OA858_RS15805 (OA858_15800) 3480162..3480440 - 279 WP_281006160.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 3464776..3496424 31648


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-90)

Antitoxin

Uncharacterized protein HI1420

(5-93)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11071.84 Da        Isoelectric Point: 9.8908

>T264926 WP_281009425.1 NZ_CP112874:c3475728-3475435 [Pseudanabaena galeata CCNP1313]
IEVRQTEIFVNWFVKLRDKKAKARIQARIDRMEMGNFGDVAPVGQGVSEMRIFYGTGYRVYFVQRGSILVILLCGGDKST
QTSDINKAKELVKQLED

Download         Length: 294 bp

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10561.13 Da        Isoelectric Point: 6.4577

>AT264926 WP_281006155.1 NZ_CP112874:c3475431-3475138 [Pseudanabaena galeata CCNP1313]
MAITTTRWNSAEHLKTEEDIQLYLEACLEEAGDAPNVIIHAFSVIARAKNMTQLAKESGLTREGLYKALSPDGNPSFATV
TKVAKALGYKLTVQPVI

Download         Length: 294 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References