Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tad-ata/Tad-HTH_37
Location 3453410..3454124 Replicon chromosome
Accession NZ_CP112874
Organism Pseudanabaena galeata CCNP1313

Toxin (Protein)


Gene name tad Uniprot ID -
Locus tag OA858_RS15670 Protein ID WP_281006139.1
Coordinates 3453410..3453781 (+) Length 124 a.a.

Antitoxin (Protein)


Gene name ata Uniprot ID -
Locus tag OA858_RS15675 Protein ID WP_281006140.1
Coordinates 3453795..3454124 (+) Length 110 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OA858_RS15640 (OA858_15635) 3449271..3450146 - 876 WP_281006133.1 alpha/beta fold hydrolase -
OA858_RS15645 (OA858_15640) 3450218..3450955 - 738 WP_281006134.1 phosphoadenylyl-sulfate reductase -
OA858_RS15650 (OA858_15645) 3451153..3451884 - 732 WP_281006135.1 NUDIX domain-containing protein -
OA858_RS15655 (OA858_15650) 3451860..3452447 - 588 WP_281006136.1 nicotinate-nucleotide adenylyltransferase -
OA858_RS15660 (OA858_15655) 3452701..3452997 + 297 WP_281006137.1 hypothetical protein -
OA858_RS15665 (OA858_15660) 3452997..3453266 + 270 WP_281006138.1 PIN domain-containing protein -
OA858_RS15670 (OA858_15665) 3453410..3453781 + 372 WP_281006139.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OA858_RS15675 (OA858_15670) 3453795..3454124 + 330 WP_281006140.1 helix-turn-helix transcriptional regulator Antitoxin
OA858_RS15680 (OA858_15675) 3454313..3454543 + 231 WP_281006141.1 hypothetical protein -
OA858_RS15685 (OA858_15680) 3454533..3454940 + 408 WP_281006142.1 DUF6516 family protein -
OA858_RS15690 (OA858_15685) 3455016..3455255 - 240 WP_281006143.1 DUF2281 domain-containing protein -
OA858_RS15695 (OA858_15690) 3455274..3455882 - 609 WP_281006144.1 hypothetical protein -
OA858_RS15700 (OA858_15695) 3455916..3457019 - 1104 WP_281006145.1 ImmA/IrrE family metallo-endopeptidase -
OA858_RS15705 (OA858_15700) 3457012..3457314 - 303 WP_281006146.1 killer suppression protein HigA -
OA858_RS15710 (OA858_15705) 3458036..3458350 + 315 WP_281006147.1 hypothetical protein -
OA858_RS15715 (OA858_15710) 3458325..3458705 + 381 WP_281006148.1 DUF6516 family protein -
OA858_RS15720 (OA858_15715) 3458815..3458961 - 147 WP_281006149.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(17-110)

Antitoxin

HigA2-like, helix-turn-helix domain

(14-93)


Sequences

Toxin        


Download         Length: 124 a.a.        Molecular weight: 13921.93 Da        Isoelectric Point: 8.0349

>T264925 WP_281006139.1 NZ_CP112874:3453410-3453781 [Pseudanabaena galeata CCNP1313]
VSSLFLKPVEWIGSSLDDLKDFPNEVQQVVGYALYIAQCGDKHPIAKPLKGFKGAGVVEVVDDFDGDTYRAVYTIKFADV
VYVLHSFQKKSKQGIATPKQDMDLIEARLKRAKEHYSEHYNKK

Download         Length: 372 bp

Antitoxin


Download         Length: 110 a.a.        Molecular weight: 12036.99 Da        Isoelectric Point: 10.2427

>AT264925 WP_281006140.1 NZ_CP112874:3453795-3454124 [Pseudanabaena galeata CCNP1313]
MTEEIKVQKSSGNVFADLGLENSDELLVKAELAYKISSIITKLEITQVEAAKLLGIDQPKMSALLNGKLSGFSTVRLFRF
LNSLGRDVEIVVKDKPKSRSQARTQVVSR

Download         Length: 330 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References