Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/MazE-MazF
Location 3102474..3103057 Replicon chromosome
Accession NZ_CP112874
Organism Pseudanabaena galeata CCNP1313

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag OA858_RS14045 Protein ID WP_281005856.1
Coordinates 3102474..3102737 (+) Length 88 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag OA858_RS14050 Protein ID WP_281009416.1
Coordinates 3102728..3103057 (+) Length 110 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OA858_RS14020 (OA858_14015) 3097597..3098661 - 1065 WP_281005852.1 TIGR00303 family protein -
OA858_RS14025 (OA858_14020) 3098888..3099154 + 267 WP_281005853.1 hypothetical protein -
OA858_RS14030 (OA858_14025) 3099294..3100439 + 1146 WP_281005854.1 Re/Si-specific NAD(P)(+) transhydrogenase subunit alpha -
OA858_RS14035 (OA858_14030) 3100544..3100834 + 291 WP_094533598.1 NAD(P) transhydrogenase subunit alpha -
OA858_RS14040 (OA858_14035) 3100841..3102253 + 1413 WP_281005855.1 NAD(P)(+) transhydrogenase (Re/Si-specific) subunit beta -
OA858_RS14045 (OA858_14040) 3102474..3102737 + 264 WP_281005856.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Toxin
OA858_RS14050 (OA858_14045) 3102728..3103057 + 330 WP_281009416.1 type II toxin-antitoxin system PemK/MazF family toxin Antitoxin
OA858_RS14055 (OA858_14050) 3103126..3104022 + 897 WP_281005857.1 ABC transporter permease -
OA858_RS14060 (OA858_14055) 3104019..3104747 + 729 WP_281005858.1 hypothetical protein -
OA858_RS14065 (OA858_14060) 3104825..3105343 - 519 WP_281005859.1 FKBP-type peptidyl-prolyl cis-trans isomerase -
OA858_RS14075 (OA858_14070) 3106133..3106651 - 519 WP_281005860.1 YdcF family protein -
OA858_RS14080 (OA858_14075) 3106796..3107392 - 597 WP_281005861.1 recombination mediator RecR -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

SpoVT-AbrB domain

(11-51)

Antitoxin

mRNA interferase PemK-like

(6-106)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 9854.21 Da        Isoelectric Point: 4.5368

>T264922 WP_281005856.1 NZ_CP112874:3102474-3102737 [Pseudanabaena galeata CCNP1313]
MGAAIRTRIIKIGNSQGIRIPKLLLEQSGIHAEVEIEVQGSHLTVRPFPQLRMGWNQAFATMAEQGDDILLDDISPTDWE
RVDWAWD

Download         Length: 264 bp

Antitoxin


Download         Length: 110 a.a.        Molecular weight: 12388.54 Da        Isoelectric Point: 9.1845

>AT264922 WP_281009416.1 NZ_CP112874:3102728-3103057 [Pseudanabaena galeata CCNP1313]
VGLNVKRFDVFLVNLDPTIGNEIQKTRPCVVISPDEMNRYISTVIIAPMTTRGRVYPTRVICQFQEKAGQIVIDQIRTVD
KTRLVKRLGQISQDEQKLVLGILAEMFAE

Download         Length: 330 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References