Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) vapBC/DUF433(antitoxin)
Location 2085967..2086538 Replicon chromosome
Accession NZ_CP112874
Organism Pseudanabaena galeata CCNP1313

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag OA858_RS09510 Protein ID WP_281009053.1
Coordinates 2085967..2086308 (-) Length 114 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag OA858_RS09515 Protein ID WP_169361944.1
Coordinates 2086305..2086538 (-) Length 78 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OA858_RS09505 (OA858_09500) 2081726..2085703 + 3978 WP_281009052.1 DNA-directed RNA polymerase subunit beta' -
OA858_RS09510 (OA858_09505) 2085967..2086308 - 342 WP_281009053.1 DUF5615 family PIN-like protein Toxin
OA858_RS09515 (OA858_09510) 2086305..2086538 - 234 WP_169361944.1 DUF433 domain-containing protein Antitoxin
OA858_RS09520 (OA858_09515) 2086662..2087120 + 459 WP_281009054.1 DUF29 domain-containing protein -
OA858_RS09525 (OA858_09520) 2087646..2088668 + 1023 WP_281009055.1 oxygen-dependent coproporphyrinogen oxidase -
OA858_RS09530 (OA858_09525) 2088831..2089814 + 984 WP_281009056.1 IS30 family transposase -
OA858_RS09535 (OA858_09530) 2090214..2090864 + 651 WP_281009393.1 DUF2079 domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(1-78)

Antitoxin

(11-66)


Sequences


Toxin        


Download         Length: 114 a.a.        Molecular weight: 12664.61 Da        Isoelectric Point: 4.2821

>T264921 WP_281009053.1 NZ_CP112874:c2086308-2085967 [Pseudanabaena galeata CCNP1313]
MIIWIDAQLPPALANWINSNFDVEAMSLKYLSLRDAKDIEIFEAARFANVVIMTKDSDFIDLVCRLGSPPRILWLTCGNV
SNRNLQRLLTATLAEALSQLEQGEVIVEISNNS

Download         Length: 342 bp


Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8672.14 Da        Isoelectric Point: 5.7661

>AT264921 WP_169361944.1 NZ_CP112874:c2086538-2086305 [Pseudanabaena galeata CCNP1313]
MNLKHSLLNRITQIAGQCGGRPCIRGMRIRVTDILEMLSENVSITEILEDFPDLELADIQACLVFAARRTDFPRLTA

Download         Length: 234 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References