Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/MazF(toxin)
Location 549422..550007 Replicon chromosome
Accession NZ_CP112874
Organism Pseudanabaena galeata CCNP1313

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag OA858_RS02455 Protein ID WP_281007778.1
Coordinates 549422..549790 (-) Length 123 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag OA858_RS02460 Protein ID WP_281007779.1
Coordinates 549783..550007 (-) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OA858_RS02430 (OA858_02425) 545923..546570 + 648 WP_281007774.1 NUDIX hydrolase -
OA858_RS02435 (OA858_02430) 546558..546692 + 135 WP_281007775.1 hypothetical protein -
OA858_RS02440 (OA858_02435) 546907..547041 - 135 WP_281007776.1 type II toxin-antitoxin system PemK/MazF family toxin -
OA858_RS02445 (OA858_02440) 547138..548199 - 1062 WP_281006032.1 IS4 family transposase -
OA858_RS02450 (OA858_02445) 548321..549142 - 822 WP_281007777.1 Uma2 family endonuclease -
OA858_RS02455 (OA858_02450) 549422..549790 - 369 WP_281007778.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
OA858_RS02460 (OA858_02455) 549783..550007 - 225 WP_281007779.1 hypothetical protein Antitoxin
OA858_RS02465 (OA858_02460) 550333..550584 + 252 WP_281007780.1 hypothetical protein -
OA858_RS02470 (OA858_02465) 550751..550972 + 222 WP_281007781.1 DUF433 domain-containing protein -
OA858_RS02475 (OA858_02470) 550976..551293 + 318 WP_281007782.1 hypothetical protein -
OA858_RS02480 (OA858_02475) 551744..552574 + 831 WP_281007783.1 hypothetical protein -
OA858_RS02485 (OA858_02480) 552698..553435 - 738 WP_281007784.1 Uma2 family endonuclease -
OA858_RS02490 (OA858_02485) 553666..554460 - 795 WP_281007785.1 Uma2 family endonuclease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(9-112)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 123 a.a.        Molecular weight: 13648.71 Da        Isoelectric Point: 9.5275

>T264920 WP_281007778.1 NZ_CP112874:c549790-549422 [Pseudanabaena galeata CCNP1313]
MPNGTLTYKRGEIWWVDLNPIVGSETGKERPCLILQNDIGNQNGLTTIVAPLLPNKKTYPFVVNVIPTPKNGLSGDRHIN
LSQMRAVDARRIKNKQGVLEDIYWKEIAKAVSIELGFNDFSS

Download         Length: 369 bp

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8656.75 Da        Isoelectric Point: 4.2092

>AT264920 WP_281007779.1 NZ_CP112874:c550007-549783 [Pseudanabaena galeata CCNP1313]
MSKKVSITLDDEVLSFVDRLASNRSSFINDILWKEKQRIFMKELENAYKEQANDPMFQEEISVWDVTVEDGLNA

Download         Length: 225 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References