264894

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hicAB/HicA(toxin)
Location 2479382..2479992 Replicon chromosome
Accession NZ_CP112867
Organism Pseudomonas quebecensis isolate S1Bt7

Toxin (Protein)


Gene name hicA Uniprot ID A0A2G0WYT7
Locus tag OSC48_RS11455 Protein ID WP_034096965.1
Coordinates 2479741..2479992 (-) Length 84 a.a.

Antitoxin (Protein)


Gene name hicB Uniprot ID -
Locus tag OSC48_RS11450 Protein ID WP_181077070.1
Coordinates 2479382..2479744 (-) Length 121 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OSC48_RS11435 (OSC48_11435) 2475474..2476304 + 831 WP_253506786.1 IclR family transcriptional regulator -
OSC48_RS11440 (OSC48_11440) 2476528..2477727 + 1200 WP_266248926.1 hypothetical protein -
OSC48_RS11445 (OSC48_11445) 2477878..2479233 + 1356 WP_181077068.1 MATE family efflux transporter -
OSC48_RS11450 (OSC48_11450) 2479382..2479744 - 363 WP_181077070.1 type II toxin-antitoxin system HicB family antitoxin Antitoxin
OSC48_RS11455 (OSC48_11455) 2479741..2479992 - 252 WP_034096965.1 type II toxin-antitoxin system HicA family toxin Toxin

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HicA mRNA interferase family

(20-76)

Antitoxin

Uncharacterised protein family HicB

(55-105)


Sequences

Toxin        


Download         Length: 84 a.a.        Molecular weight: 9497.05 Da        Isoelectric Point: 10.0458

>T264894 WP_034096965.1 NZ_CP112867:c2479992-2479741 [Pseudomonas quebecensis]
VSKNEKLLAKLLNEQMAFTWPELVTLLRRLGYTQIEGAGSRVKFDSGDPTAMITLHKPHPGNELKHYIRRQIIEQLKSGE
LIQ

Download         Length: 252 bp

Antitoxin


Download         Length: 121 a.a.        Molecular weight: 13248.06 Da        Isoelectric Point: 6.7446

>AT264894 WP_181077070.1 NZ_CP112867:c2479744-2479382 [Pseudomonas quebecensis]
VNNQLKHKGYIGSIEASLEDNCLFGKILFIKALISYEGKTVADLDAAFQEAVDDYLVTCQNLGQTPEKPCKGSFNVRVGH
DLHLAAALAATRRKVTLNDLTRQALNEFLQHHFAELHPSA

Download         Length: 363 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2G0WYT7

Antitoxin

Source ID Structure

References