Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 3358309..3358962 Replicon chromosome
Accession NZ_CP112859
Organism Acinetobacter baumannii strain EAB1

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag OPM65_RS15825 Protein ID WP_000607077.1
Coordinates 3358309..3358698 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag OPM65_RS15830 Protein ID WP_001288210.1
Coordinates 3358705..3358962 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OPM65_RS15810 (OPM65_15810) 3353427..3355622 - 2196 WP_001158906.1 TRAP transporter large permease subunit -
OPM65_RS15815 (OPM65_15815) 3355810..3356376 - 567 WP_000651538.1 rhombosortase -
OPM65_RS15820 (OPM65_15820) 3356454..3357539 - 1086 WP_000049106.1 hypothetical protein -
OPM65_RS15825 (OPM65_15825) 3358309..3358698 - 390 WP_000607077.1 membrane protein Toxin
OPM65_RS15830 (OPM65_15830) 3358705..3358962 - 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
OPM65_RS15835 (OPM65_15835) 3359150..3360322 + 1173 WP_001190542.1 acyl-CoA dehydrogenase family protein -
OPM65_RS15840 (OPM65_15840) 3360371..3361861 - 1491 WP_000415125.1 NAD(P)/FAD-dependent oxidoreductase -
OPM65_RS15845 (OPM65_15845) 3362043..3362420 - 378 WP_001216380.1 50S ribosomal protein L17 -
OPM65_RS15850 (OPM65_15850) 3362439..3363446 - 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15552.88 Da        Isoelectric Point: 10.4313

>T264887 WP_000607077.1 NZ_CP112859:c3358698-3358309 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYKSQNTV
SRVKILKIIDCQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Download         Length: 390 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT264887 WP_001288210.1 NZ_CP112859:c3358962-3358705 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References