Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 4373256..4373803 Replicon chromosome
Accession NZ_CP111121
Organism Chryseobacterium sp. MMS21-Ot14

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag ODZ84_RS20020 Protein ID WP_266174170.1
Coordinates 4373256..4373555 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag ODZ84_RS20025 Protein ID WP_266174171.1
Coordinates 4373555..4373803 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ODZ84_RS20000 (ODZ84_20000) 4368828..4369811 - 984 WP_266174165.1 GTPase ObgE -
ODZ84_RS20005 (ODZ84_20005) 4369892..4370470 - 579 WP_266174167.1 adenylate kinase -
ODZ84_RS20010 (ODZ84_20010) 4370621..4371175 - 555 WP_266174168.1 hypoxanthine phosphoribosyltransferase -
ODZ84_RS20015 (ODZ84_20015) 4371537..4373126 + 1590 WP_266174169.1 ABC-F family ATP-binding cassette domain-containing protein -
ODZ84_RS20020 (ODZ84_20020) 4373256..4373555 - 300 WP_266174170.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
ODZ84_RS20025 (ODZ84_20025) 4373555..4373803 - 249 WP_266174171.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
ODZ84_RS20030 (ODZ84_20030) 4373865..4374728 - 864 WP_266174172.1 DUF4238 domain-containing protein -
ODZ84_RS20035 (ODZ84_20035) 4374889..4376175 + 1287 WP_266174173.1 adenylosuccinate synthase -
ODZ84_RS20040 (ODZ84_20040) 4376757..4377602 + 846 WP_266174174.1 energy transducer TonB -
ODZ84_RS20045 (ODZ84_20045) 4377766..4378539 + 774 WP_266174175.1 ParA family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-92)

Antitoxin

Antitoxin ParD

(1-80)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 12230.99 Da        Isoelectric Point: 7.3121

>T264868 WP_266174170.1 NZ_CP111121:c4373555-4373256 [Chryseobacterium sp. MMS21-Ot14]
MKYRISKEASNDLEKIWLYTFEVWSKEQADHYFDLLMDEIEYLSENPKSGKDYNEIRKGYLRSRVKSHFIFYRINLKYKE
IEIIRILHQKMDISSRLDE

Download         Length: 300 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9451.69 Da        Isoelectric Point: 8.5148

>AT264868 WP_266174171.1 NZ_CP111121:c4373803-4373555 [Chryseobacterium sp. MMS21-Ot14]
MAKNTSILLGDYFDNFISQQIKSGKFSSASEVVRAALRMFEYEESKKSELISELKKGEKSGFVENFDRKEFLKNLHQKHS
AE

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References