Detailed information of TA system TA264864

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /RES-TIGR02293
• Location: 2413087..2414000
• Replicon: chromosome
• Accession: NZ_CP111115
• Organism: Raoultella sp. DY2415

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: OQV00_RS11220
• Protein ID: WP_004862779.1
• Coordinates: 2413087..2413560 (-)
• Length: 158 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: OQV00_RS11225
• Protein ID: WP_032716402.1
• Coordinates: 2413557..2414000 (-)
• Length: 148 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OQV00_RS11195	2409127..2409735	-	609	WP_069475887.1	glutathione S-transferase family protein	-
OQV00_RS11200	2409977..2410882	+	906	WP_015584186.1	transcriptional regulator GcvA	-
OQV00_RS11205	2410909..2411814	-	906	WP_044349852.1	LysR family transcriptional regulator	-
OQV00_RS11210	2411917..2412234	+	318	WP_004862785.1	nuclear transport factor 2 family protein	-
OQV00_RS11215	2412227..2413006	+	780	WP_004862782.1	SDR family oxidoreductase	-
OQV00_RS11220	2413087..2413560	-	474	WP_004862779.1	RES domain-containing protein	Toxin
OQV00_RS11225	2413557..2414000	-	444	WP_032716402.1	DUF2384 domain-containing protein	Antitoxin
OQV00_RS11230	2414190..2414756	-	567	WP_015584190.1	DJ-1/PfpI family protein	-
OQV00_RS11235	2415154..2415936	+	783	Protein_2192	DUF3750 domain-containing protein	-
OQV00_RS11240	2416133..2417356	+	1224	WP_069475891.1	zinc metallochaperone GTPase ZigA	-
OQV00_RS11260	2418286..2418762	-	477	WP_071887178.1	acid resistance repetitive basic protein Asr	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (3-148)

Antitoxin

• Antitoxin Xre/MbcA/ParS-like, toxin-binding domain (95-144)

Sequences

Toxin

Protein

• Length: 158 a.a.
• Molecular weight: 17523.84 Da
• Isoelectric Point: 5.0735

>T264864 WP_004862779.1 NZ_CP111115:c2413560-2413087 [Raoultella sp. DY2415]
MIFYRLVTGRYASEAWTGSGANQYGGRWNHQGHPAVYVSTSIALASLEILVHVKNEAILNQYQLYSIEIPNSEVESLDKQ
WLPDNWQENPMPVSTMDLGTGWLQSGSGLALMLPSCIIPYENNAILNPLHPAFSEALASVRQYPFTFDPRLARSTPL

Nucleotide

• Length: 474 bp

Antitoxin

Protein

• Length: 148 a.a.
• Molecular weight: 16176.42 Da
• Isoelectric Point: 4.9405

>AT264864 WP_032716402.1 NZ_CP111115:c2414000-2413557 [Raoultella sp. DY2415]
MKTWVPAEQPADNALWRYAGLPANRGMQLIELLSMGLPVSVLDNIHEWTEMSKTDILRITGINERNVARRKSAGGTLTPG
ESERVARFVRVLDTAVDYFGSKQDAYDWLQSPVRGLGNVAPIDLIATESGALEVTDLIGRLEHGVFA

Nucleotide

• Length: 444 bp