Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 880688..881345 Replicon chromosome
Accession NZ_CP111115
Organism Raoultella sp. DY2415

Toxin (Protein)


Gene name cptA Uniprot ID A0A808XTM6
Locus tag OQV00_RS04230 Protein ID WP_004867355.1
Coordinates 880935..881345 (+) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A514ELX1
Locus tag OQV00_RS04225 Protein ID WP_004867358.1
Coordinates 880688..880954 (+) Length 89 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OQV00_RS04200 875823..877256 - 1434 WP_004867372.1 6-phospho-beta-glucosidase -
OQV00_RS04205 877376..878104 - 729 WP_004867368.1 MurR/RpiR family transcriptional regulator -
OQV00_RS04210 878154..878465 + 312 WP_004867365.1 N(4)-acetylcytidine aminohydrolase -
OQV00_RS04215 878627..879286 + 660 WP_004867362.1 hemolysin III family protein -
OQV00_RS04220 879408..880391 - 984 WP_015585783.1 tRNA-modifying protein YgfZ -
OQV00_RS04225 880688..880954 + 267 WP_004867358.1 FAD assembly factor SdhE Antitoxin
OQV00_RS04230 880935..881345 + 411 WP_004867355.1 protein YgfX Toxin
OQV00_RS04235 881353..881874 - 522 WP_004867353.1 flavodoxin FldB -
OQV00_RS04240 882052..882948 + 897 WP_032718225.1 site-specific tyrosine recombinase XerD -
OQV00_RS04245 882971..883684 + 714 WP_004867349.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
OQV00_RS04250 883690..885423 + 1734 WP_015585785.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(3-132)

Antitoxin

(7-79)


Sequences


Toxin        


Download         Length: 137 a.a.        Molecular weight: 16226.16 Da        Isoelectric Point: 11.3349

>T264859 WP_004867355.1 NZ_CP111115:880935-881345 [Raoultella sp. DY2415]
VVLWQSDLRISWRSQWFSLLLHGIVAAIVLLMPWPLSYTPLWLLLLSLVVFDSVRSQRRIHACRGEIKLMTDSRLRWQKA
EWEIVGTPWVINSGMLLRLQDMQTRRRQHLWIAADSMDAKEWRDLRRLVLQKPAQE

Download         Length: 411 bp


Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10553.05 Da        Isoelectric Point: 4.8432

>AT264859 WP_004867358.1 NZ_CP111115:880688-880954 [Raoultella sp. DY2415]
MDITNKARIHWACRRGMRELDISIMPFFEYEYDTLSDEDKQLFIRLLENDDPDLFNWLMNHGEPADAQLQRMVKLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A808XTM6


Antitoxin

Source ID Structure
AlphaFold DB A0A514ELX1

References