Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | pmenTA/darT(toxin) |
Location | 5472384..5474110 | Replicon | chromosome |
Accession | NZ_CP111114 | ||
Organism | Pseudomonas koreensis strain FP1691 |
Toxin (Protein)
Gene name | pmenT | Uniprot ID | - |
Locus tag | OPS05_RS24730 | Protein ID | WP_096796317.1 |
Coordinates | 5472384..5473028 (+) | Length | 215 a.a. |
Antitoxin (Protein)
Gene name | pmenA | Uniprot ID | - |
Locus tag | OPS05_RS24735 | Protein ID | WP_134787420.1 |
Coordinates | 5473025..5474110 (+) | Length | 362 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
OPS05_RS24705 (OPS05_24705) | 5467787..5468599 | + | 813 | WP_027612913.1 | zinc-dependent peptidase | - |
OPS05_RS24710 (OPS05_24710) | 5468712..5469239 | + | 528 | WP_008052339.1 | inorganic diphosphatase | - |
OPS05_RS24715 (OPS05_24715) | 5469463..5470209 | + | 747 | WP_027612915.1 | helix-turn-helix transcriptional regulator | - |
OPS05_RS24720 (OPS05_24720) | 5470718..5471638 | + | 921 | WP_098965795.1 | restriction endonuclease | - |
OPS05_RS24725 (OPS05_24725) | 5471824..5472387 | + | 564 | WP_134787419.1 | DarT ssDNA thymidine ADP-ribosyltransferase family protein | - |
OPS05_RS24730 (OPS05_24730) | 5472384..5473028 | + | 645 | WP_096796317.1 | DUF4433 domain-containing protein | Toxin |
OPS05_RS24735 (OPS05_24735) | 5473025..5474110 | + | 1086 | WP_134787420.1 | macro domain-containing protein | Antitoxin |
OPS05_RS24740 (OPS05_24740) | 5474284..5474844 | + | 561 | WP_134787421.1 | hypothetical protein | - |
OPS05_RS24745 (OPS05_24745) | 5474860..5475294 | + | 435 | WP_134787422.1 | hypothetical protein | - |
OPS05_RS24750 (OPS05_24750) | 5475318..5476130 | - | 813 | WP_098965801.1 | DUF2135 domain-containing protein | - |
OPS05_RS24755 (OPS05_24755) | 5476134..5477753 | - | 1620 | WP_134787423.1 | DUF2300 domain-containing protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 215 a.a. Molecular weight: 24904.56 Da Isoelectric Point: 6.9118
>T264857 WP_096796317.1 NZ_CP111114:5472384-5473028 [Pseudomonas koreensis]
MIYTNLNPEKALIWRIVHRDNLPWILDNGLHCANSEAKAPQYVNIGNVDLIDKRRFRQVPIAPEGVLADYVPFYFTPFSV
MMQNIHSGWSVQQRGNDEIVILVSSLYRVEELGLPFVFTNAHAYPSWTNYYSDLANLDQIDWSILQRRDFKRDPDDPRKM
ERYQAEALIHQHLPITGLLGIMCHTDAMKVRIEADVAVRGLTLPVHARPKWYFQ
MIYTNLNPEKALIWRIVHRDNLPWILDNGLHCANSEAKAPQYVNIGNVDLIDKRRFRQVPIAPEGVLADYVPFYFTPFSV
MMQNIHSGWSVQQRGNDEIVILVSSLYRVEELGLPFVFTNAHAYPSWTNYYSDLANLDQIDWSILQRRDFKRDPDDPRKM
ERYQAEALIHQHLPITGLLGIMCHTDAMKVRIEADVAVRGLTLPVHARPKWYFQ
Download Length: 645 bp
Antitoxin
Download Length: 362 a.a. Molecular weight: 40668.82 Da Isoelectric Point: 6.5078
>AT264857 WP_134787420.1 NZ_CP111114:5473025-5474110 [Pseudomonas koreensis]
MIRFTQGNLLEAKTEALVNTVNTVGVMGKGIALMFKERFAQNYRLYAAACKAGDVETGKMHVTATNELDGPRWIVNFPTK
RHWRYPSQMAWITEGLHDLRRFLLENDVKSVAVPPLGAGNGGLKWPEVREQIVEVLGDLDVDVLVFEPSSQYLNVAKRDG
VEQLTPARALIAELVRRYWVLGMECSLLEIQKLAWFLERAIEKIPGTENPLNLKFVAHKFGPYANRLEHLLNNLDGSYLH
CDKRISDAGITDVIWFDQDRKTFLQTYLKTEAKEYSQALERTAELIDGFESPFGMELLATVDWLLIRERIAPTVPAVRKA
LMNWDGGSGAAVRKNKLFDDQALGIAITRLTSTSFSPEMAA
MIRFTQGNLLEAKTEALVNTVNTVGVMGKGIALMFKERFAQNYRLYAAACKAGDVETGKMHVTATNELDGPRWIVNFPTK
RHWRYPSQMAWITEGLHDLRRFLLENDVKSVAVPPLGAGNGGLKWPEVREQIVEVLGDLDVDVLVFEPSSQYLNVAKRDG
VEQLTPARALIAELVRRYWVLGMECSLLEIQKLAWFLERAIEKIPGTENPLNLKFVAHKFGPYANRLEHLLNNLDGSYLH
CDKRISDAGITDVIWFDQDRKTFLQTYLKTEAKEYSQALERTAELIDGFESPFGMELLATVDWLLIRERIAPTVPAVRKA
LMNWDGGSGAAVRKNKLFDDQALGIAITRLTSTSFSPEMAA
Download Length: 1086 bp
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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