Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 3432856..3433375 Replicon chromosome
Accession NZ_CP111114
Organism Pseudomonas koreensis strain FP1691

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag OPS05_RS15260 Protein ID WP_098964185.1
Coordinates 3432856..3433137 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A2R7MVA5
Locus tag OPS05_RS15265 Protein ID WP_003225462.1
Coordinates 3433127..3433375 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OPS05_RS15230 (OPS05_15230) 3428145..3428909 - 765 WP_027612656.1 IclR family transcriptional regulator -
OPS05_RS15235 (OPS05_15235) 3429121..3429510 - 390 WP_007912330.1 RidA family protein -
OPS05_RS15240 (OPS05_15240) 3429541..3430338 - 798 WP_097087296.1 amino acid ABC transporter ATP-binding protein -
OPS05_RS15245 (OPS05_15245) 3430335..3430997 - 663 WP_134786515.1 amino acid ABC transporter permease -
OPS05_RS15250 (OPS05_15250) 3431007..3431669 - 663 WP_134786516.1 amino acid ABC transporter permease -
OPS05_RS15255 (OPS05_15255) 3431721..3432569 - 849 WP_098964184.1 transporter substrate-binding domain-containing protein -
OPS05_RS15260 (OPS05_15260) 3432856..3433137 - 282 WP_098964185.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OPS05_RS15265 (OPS05_15265) 3433127..3433375 - 249 WP_003225462.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
OPS05_RS15270 (OPS05_15270) 3433652..3434080 + 429 WP_134786517.1 thioredoxin family protein -
OPS05_RS15275 (OPS05_15275) 3434247..3435806 - 1560 WP_134786518.1 TerC family protein -
OPS05_RS15280 (OPS05_15280) 3436222..3437868 - 1647 WP_134786519.1 phospholipase D-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10911.69 Da        Isoelectric Point: 10.6783

>T264856 WP_098964185.1 NZ_CP111114:c3433137-3432856 [Pseudomonas koreensis]
MTYELEFSEKAWREWRKLDSALQDQFKKKLSTRLVNPHVPADRLRGLGNAYKIKLRSAGYRLVYRVKNEVLVVTVIAVGR
RERGEVYDKAACR

Download         Length: 282 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9005.38 Da        Isoelectric Point: 4.5338

>AT264856 WP_003225462.1 NZ_CP111114:c3433375-3433127 [Pseudomonas koreensis]
MTHVVLSNIVASISELKRNPMGTVAAGGGQSVAILNRNEPAFYCVPAKEYEAMMNRLEDLELIALCKERENDPTIKVSID
DL

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A2R7MVA5

References