Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vapBC/- |
| Location | 2832411..2833636 | Replicon | chromosome |
| Accession | NZ_CP111114 | ||
| Organism | Pseudomonas koreensis strain FP1691 | ||
Toxin (Protein)
| Gene name | vapC | Uniprot ID | - |
| Locus tag | OPS05_RS12485 | Protein ID | WP_134786183.1 |
| Coordinates | 2832411..2833001 (-) | Length | 197 a.a. |
Antitoxin (Protein)
| Gene name | vapB | Uniprot ID | - |
| Locus tag | OPS05_RS12490 | Protein ID | WP_134786184.1 |
| Coordinates | 2833079..2833636 (-) | Length | 186 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| OPS05_RS12465 (OPS05_12465) | 2828978..2829745 | - | 768 | WP_003224391.1 | phosphonate ABC transporter, permease protein PhnE | - |
| OPS05_RS12470 (OPS05_12470) | 2829742..2830569 | - | 828 | WP_103485021.1 | ABC transporter permease subunit | - |
| OPS05_RS12475 (OPS05_12475) | 2830563..2831360 | - | 798 | WP_134786181.1 | ATP-binding cassette domain-containing protein | - |
| OPS05_RS12480 (OPS05_12480) | 2831357..2832220 | - | 864 | WP_134786182.1 | putative selenate ABC transporter substrate-binding protein | - |
| OPS05_RS12485 (OPS05_12485) | 2832411..2833001 | - | 591 | WP_134786183.1 | HD domain-containing protein | Toxin |
| OPS05_RS12490 (OPS05_12490) | 2833079..2833636 | - | 558 | WP_134786184.1 | helix-turn-helix transcriptional regulator | Antitoxin |
| OPS05_RS12495 (OPS05_12495) | 2833712..2834110 | - | 399 | WP_134786185.1 | RidA family protein | - |
| OPS05_RS12500 (OPS05_12500) | 2834233..2835177 | + | 945 | WP_134786186.1 | LysR family transcriptional regulator | - |
| OPS05_RS12505 (OPS05_12505) | 2835252..2836412 | + | 1161 | WP_134786187.1 | radical SAM protein | - |
| OPS05_RS12510 (OPS05_12510) | 2836394..2837281 | - | 888 | WP_098968390.1 | LysR substrate-binding domain-containing protein | - |
| OPS05_RS12515 (OPS05_12515) | 2837417..2838469 | + | 1053 | WP_134786188.1 | agmatine deiminase family protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 197 a.a. Molecular weight: 21835.58 Da Isoelectric Point: 4.5028
>T264855 WP_134786183.1 NZ_CP111114:c2833001-2832411 [Pseudomonas koreensis]
MNLEMIKGRLEFLREAEKLKDVLRSAHTSSGRTESTAEHSWRLCLMAIVFADQLAGLDLLKVLKMCVIHDLGEAINGDIP
AVNQAAFPDKGEQERNDLLLLTGALDEALRSEILALWDDYENAQSAEAKAVKALDKLETLLQHNQGLNPADFDYGFNLGY
GKKYTSADPVFATLRELIDQDTQQRISDGQNSNERS
MNLEMIKGRLEFLREAEKLKDVLRSAHTSSGRTESTAEHSWRLCLMAIVFADQLAGLDLLKVLKMCVIHDLGEAINGDIP
AVNQAAFPDKGEQERNDLLLLTGALDEALRSEILALWDDYENAQSAEAKAVKALDKLETLLQHNQGLNPADFDYGFNLGY
GKKYTSADPVFATLRELIDQDTQQRISDGQNSNERS
Download Length: 591 bp
Antitoxin
Download Length: 186 a.a. Molecular weight: 20444.63 Da Isoelectric Point: 10.6088
>AT264855 WP_134786184.1 NZ_CP111114:c2833636-2833079 [Pseudomonas koreensis]
MSDLLLKPALPGIALRRWRLLHRVKQTHAAQLFNVTQSTISRWESGVQAMEPAAQLQLERLLTARLDSAADQVLARLIGE
SQRPMHLICDLTHRLLACSPARAAEFTRPLSTLLGQSLWRFATPEIVLRESALATSGWHEVQAPPAVEFSTGSNASDLVP
IRAGRCRWTRIPLSDGSAARLVETL
MSDLLLKPALPGIALRRWRLLHRVKQTHAAQLFNVTQSTISRWESGVQAMEPAAQLQLERLLTARLDSAADQVLARLIGE
SQRPMHLICDLTHRLLACSPARAAEFTRPLSTLLGQSLWRFATPEIVLRESALATSGWHEVQAPPAVEFSTGSNASDLVP
IRAGRCRWTRIPLSDGSAARLVETL
Download Length: 558 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|