Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 2832411..2833636 Replicon chromosome
Accession NZ_CP111114
Organism Pseudomonas koreensis strain FP1691

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag OPS05_RS12485 Protein ID WP_134786183.1
Coordinates 2832411..2833001 (-) Length 197 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag OPS05_RS12490 Protein ID WP_134786184.1
Coordinates 2833079..2833636 (-) Length 186 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OPS05_RS12465 (OPS05_12465) 2828978..2829745 - 768 WP_003224391.1 phosphonate ABC transporter, permease protein PhnE -
OPS05_RS12470 (OPS05_12470) 2829742..2830569 - 828 WP_103485021.1 ABC transporter permease subunit -
OPS05_RS12475 (OPS05_12475) 2830563..2831360 - 798 WP_134786181.1 ATP-binding cassette domain-containing protein -
OPS05_RS12480 (OPS05_12480) 2831357..2832220 - 864 WP_134786182.1 putative selenate ABC transporter substrate-binding protein -
OPS05_RS12485 (OPS05_12485) 2832411..2833001 - 591 WP_134786183.1 HD domain-containing protein Toxin
OPS05_RS12490 (OPS05_12490) 2833079..2833636 - 558 WP_134786184.1 helix-turn-helix transcriptional regulator Antitoxin
OPS05_RS12495 (OPS05_12495) 2833712..2834110 - 399 WP_134786185.1 RidA family protein -
OPS05_RS12500 (OPS05_12500) 2834233..2835177 + 945 WP_134786186.1 LysR family transcriptional regulator -
OPS05_RS12505 (OPS05_12505) 2835252..2836412 + 1161 WP_134786187.1 radical SAM protein -
OPS05_RS12510 (OPS05_12510) 2836394..2837281 - 888 WP_098968390.1 LysR substrate-binding domain-containing protein -
OPS05_RS12515 (OPS05_12515) 2837417..2838469 + 1053 WP_134786188.1 agmatine deiminase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HD domain

(16-168)

Antitoxin

Cro/C1-type helix-turn-helix domain

(12-46)


Sequences

Toxin        


Download         Length: 197 a.a.        Molecular weight: 21835.58 Da        Isoelectric Point: 4.5028

>T264855 WP_134786183.1 NZ_CP111114:c2833001-2832411 [Pseudomonas koreensis]
MNLEMIKGRLEFLREAEKLKDVLRSAHTSSGRTESTAEHSWRLCLMAIVFADQLAGLDLLKVLKMCVIHDLGEAINGDIP
AVNQAAFPDKGEQERNDLLLLTGALDEALRSEILALWDDYENAQSAEAKAVKALDKLETLLQHNQGLNPADFDYGFNLGY
GKKYTSADPVFATLRELIDQDTQQRISDGQNSNERS

Download         Length: 591 bp

Antitoxin


Download         Length: 186 a.a.        Molecular weight: 20444.63 Da        Isoelectric Point: 10.6088

>AT264855 WP_134786184.1 NZ_CP111114:c2833636-2833079 [Pseudomonas koreensis]
MSDLLLKPALPGIALRRWRLLHRVKQTHAAQLFNVTQSTISRWESGVQAMEPAAQLQLERLLTARLDSAADQVLARLIGE
SQRPMHLICDLTHRLLACSPARAAEFTRPLSTLLGQSLWRFATPEIVLRESALATSGWHEVQAPPAVEFSTGSNASDLVP
IRAGRCRWTRIPLSDGSAARLVETL

Download         Length: 558 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References