264852

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hicAB/HicB(antitoxin)
Location 354074..354685 Replicon chromosome
Accession NZ_CP111114
Organism Pseudomonas koreensis strain FP1691

Toxin (Protein)


Gene name hicA Uniprot ID -
Locus tag OPS05_RS01545 Protein ID WP_256662070.1
Coordinates 354074..354229 (+) Length 52 a.a.

Antitoxin (Protein)


Gene name hicB Uniprot ID -
Locus tag OPS05_RS01550 Protein ID WP_134785205.1
Coordinates 354260..354685 (+) Length 142 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OPS05_RS01510 (OPS05_01510) 349196..349573 + 378 WP_134787544.1 GNAT family N-acetyltransferase -
OPS05_RS01515 (OPS05_01515) 349570..350286 + 717 WP_003220701.1 AzlC family ABC transporter permease -
OPS05_RS01520 (OPS05_01520) 350265..350582 + 318 WP_003220702.1 AzlD domain-containing protein -
OPS05_RS01525 (OPS05_01525) 350499..351425 - 927 WP_007961685.1 LysR family transcriptional regulator -
OPS05_RS01530 (OPS05_01530) 352163..352573 + 411 WP_134785202.1 MbcA/ParS/Xre antitoxin family protein -
OPS05_RS01535 (OPS05_01535) 352570..353250 + 681 WP_134785203.1 RES family NAD+ phosphorylase -
OPS05_RS01540 (OPS05_01540) 353302..353577 - 276 WP_134785204.1 DUF3077 domain-containing protein -
OPS05_RS01545 (OPS05_01545) 354074..354229 + 156 WP_256662070.1 type II toxin-antitoxin system HicA family toxin Toxin
OPS05_RS01550 (OPS05_01550) 354260..354685 + 426 WP_134785205.1 type II toxin-antitoxin system HicB family antitoxin Antitoxin
OPS05_RS01555 (OPS05_01555) 354734..354880 + 147 Protein_303 transcriptional regulator -
OPS05_RS01560 (OPS05_01560) 354985..355851 - 867 WP_134785206.1 hypothetical protein -
OPS05_RS01570 (OPS05_01570) 356463..357698 - 1236 WP_134785207.1 methyltransferase -
OPS05_RS01575 (OPS05_01575) 357679..358368 - 690 WP_007961692.1 ABC transporter permease -
OPS05_RS01580 (OPS05_01580) 358365..359060 - 696 WP_007961693.1 ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HicA mRNA interferase family

(2-49)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 52 a.a.        Molecular weight: 5486.35 Da        Isoelectric Point: 10.5756

>T264852 WP_256662070.1 NZ_CP111114:354074-354229 [Pseudomonas koreensis]
MKAQGVEFQTGKGGHFKVSLNGKSTVFPDHGAKEMGEGLRKSIIKQLGLKD

Download         Length: 156 bp

Antitoxin


Download         Length: 142 a.a.        Molecular weight: 15578.82 Da        Isoelectric Point: 4.9736

>AT264852 WP_134785205.1 NZ_CP111114:354260-354685 [Pseudomonas koreensis]
MFEYALEVHEEPGSVWLTCAEIPEMHAVGDTLEQALDTAIDAIETALSIYVDDRRLIPTGQAGEQASGVVLRLPALTAAK
VALWNTLLESGLSKAELARRLRVQRPQVDRLVDFLHHSKIENVERALQQLGRRISLSVQAA

Download         Length: 426 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References