Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /Acetyltransf_4(toxin)
Location 4170133..4171535 Replicon chromosome
Accession NZ_CP111110
Organism Pseudomonas chengduensis strain BC1815

Toxin (Protein)


Gene name - Uniprot ID A0A1H2LZG4
Locus tag OF113_RS19630 Protein ID WP_017675066.1
Coordinates 4170966..4171535 (-) Length 190 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag OF113_RS19625 Protein ID WP_247722582.1
Coordinates 4170133..4170960 (-) Length 276 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OF113_RS19610 (OF113_19610) 4167038..4167943 - 906 WP_112210251.1 GIDE domain-containing protein -
OF113_RS19615 (OF113_19615) 4167954..4168526 - 573 WP_143508653.1 LemA family protein -
OF113_RS19620 (OF113_19620) 4168717..4170054 + 1338 WP_266206946.1 imelysin family protein -
OF113_RS19625 (OF113_19625) 4170133..4170960 - 828 WP_247722582.1 AraC family transcriptional regulator Antitoxin
OF113_RS19630 (OF113_19630) 4170966..4171535 - 570 WP_017675066.1 GNAT family protein Toxin
OF113_RS19635 (OF113_19635) 4171752..4175240 + 3489 WP_266206948.1 PAS domain-containing hybrid sensor histidine kinase/response regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(14-146)

Antitoxin

DNA binding HTH domain, AraC-type

(193-270)


Sequences

Toxin        


Download         Length: 190 a.a.        Molecular weight: 21372.59 Da        Isoelectric Point: 8.0477

>T264846 WP_017675066.1 NZ_CP111110:c4171535-4170966 [Pseudomonas chengduensis]
MFKPQLVTLQRGALRLEPLSDADIPALVALAEANREELLYMSGTQRLDWYRSALADMREQRALPFVIRLGDELVGTTRFA
DFMNTLPACEIGWTWLDRGQHGSGLNTSIKYLMLKHAFENWGMVRVQLKTAASNLRSQRAIEKLGAVREGLLRNHRRLAD
GRLDDTVLYSITDLEWPALRGAMEAGFNA

Download         Length: 570 bp

Antitoxin


Download         Length: 276 a.a.        Molecular weight: 30751.16 Da        Isoelectric Point: 8.7310

>AT264846 WP_247722582.1 NZ_CP111110:c4170960-4170133 [Pseudomonas chengduensis]
MHSREQTRFWQASALSGVELLQARYLEQRFAPHVHEGFVFTVIEHGAQRFRHRGCDHLAPQGSMVLINPDEVHTGSKAHE
DGWRYRGFYPDNVQVLGALQELGLAKAGMPSFAFSVLHDPRLHAAFLQLHQLLEGGAEALQQQLAWREAILLLFQHHAQL
AEPPAPGREPWAVACAKQMLAERLVEPPSLEELAAAVSLSPFHFARVFRRATGLPPHAWLKQRRLEQARALLKTGCTAVA
VAMQLGFADQSHLSRQFKQVYGVSPGEYRSAVARS

Download         Length: 828 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1H2LZG4

Antitoxin

Source ID Structure

References