264845

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 4044532..4046264 Replicon chromosome
Accession NZ_CP111110
Organism Pseudomonas chengduensis strain BC1815

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag OF113_RS18995 Protein ID WP_266206886.1
Coordinates 4044532..4045173 (+) Length 214 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag OF113_RS19000 Protein ID WP_266206887.1
Coordinates 4045173..4046264 (+) Length 364 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OF113_RS18970 (OF113_18970) 4040216..4041016 + 801 WP_266206882.1 phosphonate ABC transporter ATP-binding protein -
OF113_RS18975 (OF113_18975) 4041010..4041837 + 828 WP_266206883.1 ABC transporter permease -
OF113_RS18980 (OF113_18980) 4041834..4042595 + 762 WP_266206884.1 phosphonate ABC transporter, permease protein PhnE -
OF113_RS18985 (OF113_18985) 4042789..4043490 + 702 WP_266206885.1 hypothetical protein -
OF113_RS18990 (OF113_18990) 4044044..4044535 + 492 WP_266208617.1 DarT ssDNA thymidine ADP-ribosyltransferase family protein -
OF113_RS18995 (OF113_18995) 4044532..4045173 + 642 WP_266206886.1 DUF4433 domain-containing protein Toxin
OF113_RS19000 (OF113_19000) 4045173..4046264 + 1092 WP_266206887.1 macro domain-containing protein Antitoxin
OF113_RS19005 (OF113_19005) 4046524..4047123 + 600 WP_266206888.1 DUF5131 family protein -
OF113_RS19010 (OF113_19010) 4047033..4048061 + 1029 WP_100774681.1 IS30 family transposase -
OF113_RS19015 (OF113_19015) 4048036..4048428 + 393 WP_266206889.1 DUF5131 family protein -
OF113_RS19020 (OF113_19020) 4048456..4049697 + 1242 WP_266206890.1 three-Cys-motif partner protein TcmP -
OF113_RS19025 (OF113_19025) 4049926..4050726 + 801 WP_266206891.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 4047120..4048061 941


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(14-213)

Antitoxin

Macro domain

(18-130)


Sequences

Toxin        


Download         Length: 214 a.a.        Molecular weight: 25196.82 Da        Isoelectric Point: 8.8683

>T264845 WP_266206886.1 NZ_CP111110:4044532-4045173 [Pseudomonas chengduensis]
MIYNSLNPEKALIWRIVHRDNLPWILDNGLHCANSGVLSPNYVNIGNPDLIDKRRHRAVPIAPRGTLADYVPFYFTPFSV
MMKNIHSGWSVQQRRNEEIVILVSSLHRIEELGLPFVFTNAHAYPHWTSYYSDLERLNQIDWSILQHRDFKRDPDDPRKM
ERYQAEALVYRHLPIEGLMGVICYTDAVKRRIEQEIQRRNLNLSVHTRTGWYF

Download         Length: 642 bp

Antitoxin


Download         Length: 364 a.a.        Molecular weight: 41169.18 Da        Isoelectric Point: 5.7143

>AT264845 WP_266206887.1 NZ_CP111110:4045173-4046264 [Pseudomonas chengduensis]
MIRYTQGNLLEAKVEALVNTVNTVGVMGKGIALMFKERFAENFLLYASACKAKQVQTGKMFITEVRELDGPRWVINFPTK
RHWRSPSQMAWITEGLEDLRNFLIENQVKSIAIPPLGAGNGGLEWDAVREHIEATLSDLETEILVFEPTKQYQNVAKRSG
VEKLTPARALIAELVRRYWVLGMECSLLEIQKLAWFLERAIDRCASVENPLKLQFVAHKYGPYANRLDHLLNNLDGSYLH
CDKRISDAGPLDVIWFNDERKAFVQTYLRSEAKAYVPALEYTAALIDGFESPYGMELLATVDWLLTRENIEPTVIALREG
LQHWSGGQGAAERKNGLFDDHSLEIALQRLTQPKPSFDEVSTQ

Download         Length: 1092 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References